ArticleJournal of veterinary emergency and critical care (San Antonio, Tex. : 2001)2022
Prospective evaluation of novel biomarkers of acute kidney injury in dogs following cardiac surgery under cardiopulmonary bypass.
Article in Journal of veterinary emergency and critical care (San Antonio, Tex. : 2001), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 1 of them a synthesis that pooled it.
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
8 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Beyond traditional biomarkers: do serum cystatin C and urinary cystatin B improve diagnostic precision in feline and canine renal disease? A systematic review and meta-analysis.Frontiers in veterinary science · 2026Pooled it
- Urinary symmetric dimethylarginine: A promising biomarker for acute kidney injury in dogs with pyometra.The Veterinary record · 2026Article
- Anaesthetic management and peri-anaesthetic morbidity and mortality in a population of 176 dogs undergoing mitral valve repair under cardiopulmonary bypass.Frontiers in veterinary science · 2026Article
- Renal Biomarkers in Companion Animals-A Review.Animals : an open access journal from MDPI · 2025Review
- A Clinical Study on Urinary Clusterin and Cystatin B in Dogs with Spontaneous Acute Kidney Injury.Veterinary sciences · 2024Article
- Prospective evaluation of novel biomarkers of acute kidney injury in dogs following cardiac surgery under cardiopulmonary bypass.Journal of veterinary emergency and critical care (San Antonio, Tex. : 2001) · 2022Article
- Retrospective Evaluation of Acute Postoperative Complications Occurring in the ICU Following Canine Mitral Valve Repair Surgery Under Cardiopulmonary Bypass (2019-2020): 41 Cases.Journal of veterinary emergency and critical care (San Antonio, Tex. : 2001)Article
- Urinary cystatin B differentiates progressive versus stable IRIS Stage 1 chronic kidney disease in dogs.Journal of veterinary internal medicineArticle
Corrections and comments
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Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveTo assess the occurrence of acute kidney injury (AKI) in dogs undergoing cardiac surgery under cardiopulmonary bypass (CPB) and explore associations between traditional and novel serum and urinary biomarkers.
designProspective cohort study conducted between July 2018 and April 2019.
settingUniversity teaching hospital. ANIMALS: Nineteen dogs undergoing cardiac surgery under CPB with preoperative serum creatinine <140 μmol/L (<1.6 mg/dl).
interventionsBlood and urine samples were obtained at 4 time points: preoperatively following general anesthesia induction, immediately postoperatively, and 2 and 4 days postoperatively (T MEASUREMENTS AND MAIN
resultsAKI occurred in 3 of 19 dogs (15.8%, 95% confidence interval: 0.047-0.384). Inosine increased at T
conclusionsInosine and uCysB concentrations changed in all dogs immediately following a surgery under CPB and may indicate tubular injury. Further studies are required to ascertain the usefulness of those biomarkers in early detection of AKI.
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Registered trials
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