Evidence map›Paper›PMID 36125292›Full record

ReviewAmerican journal of human biology : the official journal of the Human Biology Council2023

Adverse heat-health outcomes and critical environmental limits (Pennsylvania State University Human Environmental Age Thresholds project).

S Tony Wolf, Daniel J Vecellio, W Larry Kenney

Open access · greenAbstract readReview
In one paragraph

Review in American journal of human biology : the official journal of the Human Biology Council, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.1field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 10 citations in OpenAlex.

  1. Validating new limits for human thermoregulation.Proceedings of the National Academy of Sciences of the United States of America · 2025
    Article
  2. Article
  3. Extreme climatic events and human biology and health: A primer and opportunities for future research.American journal of human biology : the official journal of the Human Biology Council · 2023
    Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

S Tony WolfDepartment of Kinesiology, The Pennsylvania State University, University Park, Pennsylvania, United States.ORCID 0000-0002-6336-2143
Daniel J VecellioCenter for Healthy Aging, The Pennsylvania State University, University Park, Pennsylvania, United States.
W Larry KenneyDepartment of Kinesiology, The Pennsylvania State University, University Park, Pennsylvania, United States.
Pennsylvania State University · US

Funding

Psychosocial Determinants and Biological Pathway to Healthy Aging (Pathways)T32AG049676 · NIA · PENNSYLVANIA STATE UNIVERSITY, THE · PI LYNN M. MARTIRE · 2016 to 2026
$3.9M
Identification of Critical Thermal Environments for Aged AdultsR01AG067471 · NIA · PENNSYLVANIA STATE UNIVERSITY, THE · PI KENNEY, W. LARRY · 2020 to 2024
$3.7M
NIA NIH HHS R01 AG067471NIA NIH HHS T32 AG049676
6 · The paper itself

Abstract

backgroundThe earth's climate is warming and the frequency, duration, and severity of heat waves are increasing. Meanwhile, the world's population is rapidly aging. Epidemiological data demonstrate exponentially greater increases in morbidity and mortality during heat waves in adults ≥65 years. Laboratory data substantiate the mechanistic underpinnings of age-associated differences in thermoregulatory function. However, the specific combinations of environmental conditions (i.e., ambient temperature and absolute/relative humidity) above which older adults are at increased risk of heat-related morbidity and mortality are less clear.

methodsThis review was conducted to (1) examine the recent (past 3 years) literature regarding heat-related morbidity and mortality in the elderly and discuss projections of future heat-related morbidity and mortality based on climate model data, and (2) detail the background and unique methodology of our ongoing laboratory-based projects aimed toward identifying the specific environmental conditions that result in elevated risk of heat illness in older adults, and the implications of using the data toward the development of evidence-based safety interventions in a continually-warming climate (PSU HEAT; Human Environmental Age Thresholds).

resultsThe recent literature demonstrates that extreme heat continues to be increasingly detrimental to the health of the elderly and that this is apparent across the world, although the specific environmental conditions above which older adults are at increased risk of heat-related morbidity and mortality remain unclear.

conclusionCharacterizing the environmental conditions above which risk of heat-related illnesses increase remains critical to enact policy decisions and mitigation efforts to protect vulnerable people during extreme heat events.

Indexed as

Extreme HeatHot TemperatureAgedHumansOutcome Assessment, Health CarePennsylvaniaUniversities

Identifiers

PMID36125292
PMCPMC9840654
OpenAlexW4297855388

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.