ArticleMicrobiology spectrum2022
Decreased Sensitivity of Rapid Antigen Test Is Associated with a Lower Viral Load of Omicron than Delta SARS-CoV-2 Variant.
Article in Microbiology spectrum, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
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Who cites it
14 citing papers in PubMed, 27 citations in OpenAlex.
- The establishment of a universal standard for both viral antigen and nucleid acid detection based on digital PCR.Virology journal · 2025Article
- Comparison of the analytical and clinical sensitivities of 34 rapid antigen tests with prevalent SARS-CoV-2 variants of concern during the COVID-19 pandemic in the UK.Microbiology spectrum · 2025Article
- Comprehensive Study of the IBMP ELISA IgA/IgM/IgG COVID-19 Kit for SARS-CoV-2 Antibody Detection.Diagnostics (Basel, Switzerland) · 2024Article
- Proceedings of the Clinical Microbiology Open 2023: discussions about pandemic preparedness.Journal of clinical microbiology · 2024Review
- Article
- The sensitivity and specificity of Abbott Panbio™ COVID 19 Ag Rapid test in the context of four SARS-CoV-2 variants.Heliyon · 2024Article
- Standardization and Comparison of Emergency Use Authorized COVID-19 Assays and Testing Laboratories.medRxiv : the preprint server for health sciences · 2023Article
- Automated antigen assays display a high heterogeneity for the detection of SARS-CoV-2 variants of concern, including several Omicron sublineages.Medical microbiology and immunology · 2023Article
- Mathematical modeling for Delta and Omicron variant of SARS-CoV-2 transmission dynamics in Greece.Infectious Disease Modelling · 2023Article
- Regional Evaluation of Two SARS-CoV-2 Antigen Rapid Diagnostic Tests in East Africa.Microbiology spectrum · 2023Article
- Sensitivity of rapid antigen tests for Omicron subvariants of SARS-CoV-2.Journal of medical virology · 2023Article
- Article
- Exhaled Breath Aerosol Shedding of Highly Transmissible Versus Prior Severe Acute Respiratory Syndrome Coronavirus 2 Variants.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2023Article
- Evaluation of Four Rapid Antigen Tests for the Detection of SARS-CoV-2 Infection with Nasopharyngeal Swabs.Biomedicines · 2023Article
Corrections and comments
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Authors and funding
12 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Large-scale screening for SARS-CoV-2 infection is an important tool for epidemic prevention and control. The appearance of new variants associated with specific mutations can call into question the effectiveness of rapid diagnostic tests (RDTs) deployed massively at national and international levels. We compared the clinical and virological characteristics of individuals infected by Delta or Omicron variants to assess which factors were associated with a reduced performance of RDT. A commercially available RDT as well as the evaluation of the viral load (VL) and the detection of replicate intermediates (RIs) were carried out retrospectively on positive SARS-CoV-2 nasopharyngeal specimens from health care workers of the Pitié-Salpêtrière Hospital infected by the Delta or Omicron variant between July 2021 and January 2022. Of the 205 samples analyzed (104 from individuals infected with Delta and 101 with Omicron), 176 were analyzed by RDT and 200 by RT-PCR for VL and RIs. The sensitivity of the TDR for Omicron was significantly lower than that observed for Delta (53.8%
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