ArticleeLife2022
Stability of motor representations after paralysis.
Article in eLife, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
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Who cites it
12 citing papers in PubMed, 20 citations in OpenAlex.
- Targeting grasp-related cortical areas for intracortical brain-machine interfaces.Neuroimage. Reports · 2026Article
- Progress on Omega-3 fatty acids for the comprehensive and targeted treatment of spinal cord injury.Bone research · 2026Review
- Decoding multi-joint hand movements from brain signals by learning a synergy-based neural manifold.Patterns (New York, N.Y.) · 2025Article
- TMS-Based Neurofeedback Training of Mental Finger Individuation Induces Neuroplastic Changes in the Sensorimotor System.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2025Article
- Enhanced control of a brain-computer interface by tetraplegic participants via neural-network-mediated feature extraction.Nature biomedical engineering · 2025Article
- Pseudo-linear summation explains neural geometry of multi-finger movements in human premotor cortex.Nature communications · 2025Article
- A novel robot-assisted method for implanting intracortical sensorimotor devices for brain-computer interface studies: principles, surgical techniques, and challenges.Journal of neurosurgery · 2025Article
- Motor somatotopy impacts imagery strategy success in human intracortical brain-computer interfaces.Journal of neural engineering · 2025Article
- Decoding Single and Paired Phonemes Using 7T Functional MRI.Brain topography · 2024Article
- Motor somatotopy impacts imagery strategy success in human intracortical brain-computer interfaces.medRxiv : the preprint server for health sciences · 2024Article
- Performing a vibrotactile discrimination task modulates finger representations in primary somatosensory cortex.Journal of neurophysiology · 2023Article
- Decoding and geometry of ten finger movements in human posterior parietal cortex and motor cortex.Journal of neural engineering · 2023Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors at 4 institutions in 2 countries.
Funding
Abstract
Neural plasticity allows us to learn skills and incorporate new experiences. What happens when our lived experiences fundamentally change, such as after a severe injury? To address this question, we analyzed intracortical population activity in the posterior parietal cortex (PPC) of a tetraplegic adult as she controlled a virtual hand through a brain-computer interface (BCI). By attempting to move her fingers, she could accurately drive the corresponding virtual fingers. Neural activity during finger movements exhibited robust representational structure similar to fMRI recordings of able-bodied individuals' motor cortex, which is known to reflect able-bodied usage patterns. The finger representational structure was consistent throughout multiple sessions, even though the structure contributed to BCI decoding errors. Within individual BCI movements, the representational structure was dynamic, first resembling muscle activation patterns and then resembling the anticipated sensory consequences. Our results reveal that motor representations in PPC reflect able-bodied motor usage patterns even after paralysis, and BCIs can re-engage these stable representations to restore lost motor functions.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.