ArticleJournal of the American Medical Informatics Association : JAMIA2022
Computer clinical decision support that automates personalized clinical care: a challenging but needed healthcare delivery strategy.
Abstract read
In one paragraph
Article in Journal of the American Medical Informatics Association : JAMIA, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
10 citing papers in PubMed.
- Letter to the Editor: Bridging the Intention-Action Gap: Future Directions for Implementing Acceptable and Feasible Comfort Rounding.Journal of advanced nursing · 2026Article
- Nurses' Knowledge of Insensible Water Loss and the Evolution of a Digital Decision-Support Tool for Personalized Fluid Balance Assessment: A Cross-Sectional Study.Journal of personalized medicine · 2026Article
- Implementing a closed loop clinical decision support system for sustainable preoperative care.NPJ digital medicine · 2025Article
- The role of artificial intelligence in life-sustaining treatment decisions: current state and future considerations.Intensive care medicine · 2025Article
- Clinical practice, decision-making, and use of clinical decision support systems in invasive mechanical ventilation: a narrative review.British journal of anaesthesia · 2024Review
- Prognosticating the outcome of intensive care in older patients-a narrative review.Annals of intensive care · 2024Review
- Personalizing renal replacement therapy initiation in the intensive care unit: a reinforcement learning-based strategy with external validation on the AKIKI randomized controlled trials.Journal of the American Medical Informatics Association : JAMIA · 2024Article
- How will AI make sense of our messy lives and improve our mental health?Frontiers in psychiatry · 2024Article
- A voice-based digital assistant for intelligent prompting of evidence-based practices during ICU rounds.Journal of biomedical informatics · 2023Article
- Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
70 authors.
Alan H MorrisDepartment of Internal Medicine, University of Utah, Salt Lake City, Utah, USA.ORCID 0000-0001-7005-7924
Christopher HorvatDepartment of Critical Care Medicine, University of Pittsburgh, Pittsburgh, Pennsylvania, USA.
Brian StaggDepartment of Ophthalmology and Visual Sciences, Moran Eye Center, University of Utah, Salt Lake City, Utah, USA.
David W GraingerDepartment of Biomedical Engineering, University of Utah, Salt Lake City, Utah, USA.
Michael LanspaDepartment of Internal Medicine, Intermountain Healthcare, Salt Lake City, Utah, USA.
James OrmeDepartment of Internal Medicine, University of Utah, Salt Lake City, Utah, USA.
Terry P ClemmerDepartment of Internal Medicine (Critical Care), Intermountain Healthcare, Salt Lake City, Utah, USA.
Lindell K WeaverDepartment of Internal Medicine, Intermountain Healthcare, Salt Lake City, Utah, USA.
Frank O ThomasDepartment of Internal Medicine, University of Utah, Salt Lake City, Utah, USA.
Colin K GrissomDepartment of Internal Medicine, Intermountain Healthcare, Salt Lake City, Utah, USA.
Ellie HirshbergDepartment of Internal Medicine, Intermountain Healthcare, Salt Lake City, Utah, USA.
Thomas D EastSYNCRONYS - Chief Executive Officer, Albuquerque, New Mexico, USA.
Carrie Jane WallaceDepartment of Internal Medicine, Intermountain Healthcare, Salt Lake City, Utah, USA.
Michael P YoungDepartment of Critical Care, Renown Regional Medical Center, Reno, Nevada, USA.
Dean F SittigSchool of Biomedical Informatics, University of Texas Health Science Center, Houston, Texas, USA.ORCID 0000-0001-5811-8915
Mary SuchytaDepartment of Internal Medicine, Intermountain Healthcare, Salt Lake City, Utah, USA.
James E PearlDepartment of Internal Medicine, University of Utah, Salt Lake City, Utah, USA.
Antinio PesentiFaculty of Medicine and Surgery-Anesthesiology, University of Milan, Milano, Lombardia, Italy.
Michela BombinoDepartment of Emergency and Intensive Care, San Gerardo Hospital, Monza (MB), Italy.
Eduardo BeckFaculty of Medicine and Surgery - Anesthesiology, University of Milan, Ospedale di Desio, Desio, Lombardia, Italy.
Katherine A SwardDepartment of Biomedical Informatics, College of Nursing, University of Utah, Salt Lake City, Utah, USA.ORCID 0000-0002-6568-4031
Charlene WeirDepartment of Biomedical Informatics, University of Utah, Salt Lake City, Utah, USA.ORCID 0000-0002-8297-2860
Shobha PhansalkarWolters Kluwer Health-Clinical Solutions-Medical Informatics, Wolters Kluwer Health, Newton, Massachusetts, USA.
Gordon R BernardVanderbilt University School of Medicine, Nashville, Tennessee, USA.
B Taylor ThompsonPulmonary and Critical Care Division, Department of Internal Medicine, Harvard Medical School, Boston, Massachusetts, USA.
Roy BrowerDepartment of Medicine, Johns Hopkins School of Medicine, Baltimore, Maryland, USA.
Jonathon TruwitDepartment of Internal Medicine, Pulmonary and Critical Care, Medical College of Wisconsin, Milwaukee, Wisconsin, USA.
Jay SteingrubDepartment of Internal Medicine, Pulmonary and Critical Care, University of Massachusetts Medical School, Baystate Campus, Springfield, Massachusetts, USA.
R Duncan HitenDepartment of Internal Medicine, Pulmonary and Critical Care, University of Cincinnati College of Medicine, Cincinnati, Ohio, USA.
Douglas F WillsonPediatric Critical Care, Department of Pediatrics, Virginia Commonwealth University, Richmond, Virginia, USA.
Jerry J ZimmermanDivision of Pediatric Critical Care Medicine, Department of Pediatrics, University of Washington School of Medicine, Seattle, Washington, USA.
Vinay NadkarniDepartment of Anesthesiology and Critical Care Medicine, The Children's Hospital of Philadelphia, Philadelphia, Pennsylvania, USA.
Adrienne G RandolphDepartment of Anesthesiology, Critical Care and Pain Medicine, Boston Children's Hospital, Boston, Massachusetts, USA.
Martha A Q CurleyUniversity of Pennsylvania School of Nursing, Philadelphia, Pennsylvania, USA.
Christopher J L NewthChildrens Hospital Los Angeles, Department of Anesthesiology and Critical Care, University of Southern California Keck School of Medicine, Los Angeles, California, USA.
Jacques LacroixDivision of Pediatric Critical Care Medicine, Department of Pediatrics, Université de Montréal Faculté de Médecine, Montreal, Quebec, Canada.
Michael S D AgusDivision of Medical Pediatric Critical Care, Department of Pediatrics, Boston Children's Hospital, Harvard Medical School, Boston, Massachusetts, USA.
Kang Hoe LeeDepartment of Intensive Care Medicine, Ng Teng Fong Hospital and National University Centre of Transplantation, National University Singapore Yong Loo Lin School of Medicine, Singapore.
Bennett P deBoisblancDepartment of Internal Medicine, Pulmonary and Critical Care, Louisiana State University Health Sciences Center, New Orleans, Louisiana, USA.
Frederick Alan MooreDepartment of Surgery, University of Florida College of Medicine, Gainesville, Florida, USA.
R Scott EvansDepartment of Medical Informatics, Intermountain Healthcare, and Department of Biomedical Informatics, University of Utah, Salt Lake City, Utah, USA.
Dean K SorensonDepartment of Medical Informatics, Intermountain Healthcare, Salt Lake City, Utah, USA.
Anthony WongDepartment of Data Science Ann and Robert H Lurie Children's Hospital of Chicago, Chicago, Illinois, USA.
Michael V BolandDepartment of Ophthalmology, Massachusetts Ear and Eye Infirmary, Harvard Medical School, Boston, Massachusetts, USA.
Willard H DereEndocrinology and Metabolism Division, Department of Internal Medicine, University of Utah, Salt Lake City, Utah, USA.
Alan CrandallDepartment of Ophthalmology and Visual Sciences, Moran Eye Center, University of Utah, Salt Lake City, Utah, USA.
Julio FacelliDepartment of Biomedical Informatics, University of Utah, Salt Lake City, Utah, USA.
Stanley M HuffDepartment of Medical Informatics, Intermountain Healthcare, Department of Biomedical Informatics, University of Utah, and Graphite Health, Salt Lake City, Utah, USA.ORCID 0000-0001-8595-2665
Peter J HaugDepartment of Medical Informatics, Intermountain Healthcare, and Department of Biomedical Informatics, University of Utah, Salt Lake City, Utah, USA.
Ulrike PielmeierAalborg University Faculty of Engineering and Science - Department of Health Science and Technology, Respiratory and Critical Care Group, Aalborg, Nordjylland, Denmark.
Stephen E ReesAalborg University Faculty of Engineering and Science - Department of Health Science and Technology, Respiratory and Critical Care Group, Aalborg, Nordjylland, Denmark.
Dan S KarbingAalborg University Faculty of Engineering and Science - Department of Health Science and Technology, Respiratory and Critical Care Group, Aalborg, Nordjylland, Denmark.
Steen AndreassenAalborg University Faculty of Engineering and Science - Department of Health Science and Technology, Respiratory and Critical Care Group, Aalborg, Nordjylland, Denmark.
Eddy FanInternal Medicine, Pulmonary and Critical Care Division, Institute of Health Policy, Management and Evaluation, University of Toronto Faculty of Medicine, Toronto, Ontario, Canada.
Roberta M GoldringDepartment of Internal Medicine, Pulmonary and Critical Care, New York University School of Medicine, New York, New York, USA.
Kenneth I BergerDepartment of Internal Medicine, Pulmonary and Critical Care, New York University School of Medicine, New York, New York, USA.
Beno W OppenheimerDepartment of Internal Medicine, Pulmonary and Critical Care, New York University School of Medicine, New York, New York, USA.
E Wesley ElyInternal Medicine, Pulmonary and Critical Care, Critical Illness, Brain Dysfunction, and Survivorship (CIBS) Center, Vanderbilt University Medical Center, Nashville, Tennessee, USA.
Brian W PickeringDepartment of Anesthesiology, Mayo Clinic, Rochester, Minnesota, USA.
David A SchoenfeldBiostatistics Center, Massachusetts General Hospital, Boston, Massachusetts, USA.
Irena TocinoDepartment of Radiology, Yale University School of Medicine, New Haven, Connecticut, USA.
Russell S GonneringDepartment of Ophthalmology and Visual Sciences, Medical College of Wisconsin, Milwaukee, Wisconsin, USA.ORCID 0000-0002-5228-7512
Peter J PronovostDepartment of Anesthesiology and Critical Care Medicine, University Hospitals, Highland Hills, Case Western Reserve University School of Medicine, Cleveland, Ohio, USA.
Lucy A SavitzNorthwest Center for Health Research, Kaiser Permanente, Oakland, California, USA.
Didier DreyfussAssistance Publique-Hôpitaux de Paris, Université de Paris, Sorbonne Université - INSERM unit UMR S_1155 (Common and Rare Kidney Diseases), Paris, France.
Arthur S SlutskyInterdepartmental Division of Critical Care Medicine, Keenan Research Center, Li Ka Shing Knowledge Institute, St. Michael's Hospital, University of Toronto, Toronto, Ontario, Canada.
James D CrapoDepartment of Internal Medicine, National Jewish Health, Denver, Colorado, USA.
Michael R PinskyDepartment of Critical Care Medicine, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA.
Brent JamesDepartment of Internal Medicine, Clinical Excellence Research Center (CERC), Stanford University School of Medicine, Stanford, California, USA.
Donald M BerwickInstitute for Healthcare Improvement, Cambridge, Massachusetts, USA.
Funding
Yale Clinical and Translational Science Award (U Component)UL1TR001863 · NCATS · YALE UNIVERSITY · PI John H. Krystal, LUCILA OHNO-MACHADO · 2016 to 2026
$102.9MUtah Center for Clinical and Translational ScienceUL1TR002538 · NCATS · UNIVERSITY OF UTAH · PI HESS, RACHEL, MAJERSIK, JENNIFER JUHL · 2018 to 2022
$26.0MTreatment of Acute Lung Injury and Acute Respiratory Distress SyndromeN01HR56179 · NHLBI · MASSACHUSETTS GENERAL HOSPITAL · PI SCHOENFELD, DAVID A · 2007 to 2014
$7.5MTreatment of Acute Lung Injury and Acute Respiratory Distress SyndromeN01HR56170 · NHLBI · JOHNS HOPKINS UNIVERSITY · PI BROWER, ROY G. · 2007 to 2014
$2.6MTreatment of Acute Lung Injury and Acute Respiratory Distress SyndromeN01HR56175 · NHLBI · WAKE FOREST UNIVERSITY HEALTH SCIENCES · PI HITE, DUNCAN · 2007 to 2014
$2.6MTreatment of Acute Lung Injury and Acute Respiratory Distress SyndromeN01HR56171 · NHLBI · IHC HEALTH SERVICES, INC. · PI MORRIS, ALAN H · 2007 to 2014
$2.4MImproving Glaucoma Care Using a Scalable Decision Support SystemK23EY032577 · NEI · UTAH STATE HIGHER EDUCATION SYSTEM--UNIVERSITY OF UTAH · PI Brian Stagg · 2022 to 2026
$1.3MVITAMIN C, GLUTATHIONE, AND ENDOTHELIAL CELL FUNCTIONR01HL056170 · NHLBI · OREGON STATE UNIVERSITY · PI FREI, BALZ B · 1996 to 1999
–Clin Coord Ctr for Clin Ntwrk Treatment of ARDS-268056179-268056179N01HR056179 · HR · MASSACHUSETTS GENERAL HOSPITAL · PI SCHOENFELD, DAVID · 2005 to 2006
–Re-Engineering the Clinical Research EnterpriseN01HC045210 · HC · LDS HOSPITAL · PI MORRIS, ALAN H · 2004 to 2004
–NCATS NIH HHS UL1 TR001863NCATS NIH HHS UL1 TR002538NEI NIH HHS K23 EY032577NHLBI NIH HHS N01 HC045210NHLBI NIH HHS N01HC45210NHLBI NIH HHS N01 HR056165NHLBI NIH HHS N01 HR056170NHLBI NIH HHS N01 HR056171NHLBI NIH HHS N01 HR056175NHLBI NIH HHS N01 HR056179NHLBI NIH HHS N01HR56170NHLBI NIH HHS N01HR56171NHLBI NIH HHS N01HR56175NHLBI NIH HHS N01HR56179NIH HHS HL36787
Abstract
How to deliver best care in various clinical settings remains a vexing problem. All pertinent healthcare-related questions have not, cannot, and will not be addressable with costly time- and resource-consuming controlled clinical trials. At present, evidence-based guidelines can address only a small fraction of the types of care that clinicians deliver. Furthermore, underserved areas rarely can access state-of-the-art evidence-based guidelines in real-time, and often lack the wherewithal to implement advanced guidelines. Care providers in such settings frequently do not have sufficient training to undertake advanced guideline implementation. Nevertheless, in advanced modern healthcare delivery environments, use of eActions (validated clinical decision support systems) could help overcome the cognitive limitations of overburdened clinicians. Widespread use of eActions will require surmounting current healthcare technical and cultural barriers and installing clinical evidence/data curation systems. The authors expect that increased numbers of evidence-based guidelines will result from future comparative effectiveness clinical research carried out during routine healthcare delivery within learning healthcare systems.
Indexed as
Decision Support Systems, ClinicalComputersDelivery of Health Careautomated clinical careclinicalcliniciansclosed-loopcomputersdecision-support
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What OpenQuestion holds
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Registered trials
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.