ArticleNeurorehabilitation and neural repair2022
Methodological Recommendations for Studies on the Daily Life Implementation of Implantable Communication-Brain-Computer Interfaces for Individuals With Locked-in Syndrome.
Article in Neurorehabilitation and neural repair, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
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Who cites it
15 citing papers in PubMed, 14 citations in OpenAlex.
- Article
- Association between motor cortex grey matter loss and inability to control an ECoG-based implanted Brain-Computer Interface in ALS.medRxiv : the preprint server for health sciences · 2026Article
- Ethical Guidance for Investigational Implantable Neural Device Studies: Recommendations for Researchers and Research Ethics Committees.Neuromodulation : journal of the International Neuromodulation Society · 2026Review
- Optimal location for gesture decoding in the sensorimotor cortex and implications for brain-computer interface research.NeuroImage · 2026Article
- [Research progress on flexible electrode technology in brain computer interface applications].Sheng wu yi xue gong cheng xue za zhi = Journal of biomedical engineering = Shengwu yixue gongchengxue zazhi · 2026Review
- Brain-computer interfaces: a new horizon in communication for locked-in syndrome.Annals of medicine and surgery (2012) · 2025Article
- Large-scale fMRI dataset for the design of motor-based Brain-Computer Interfaces.Scientific data · 2025Article
- Mind the gap: bridging ethical considerations and regulatory oversight in implantable BCI human subjects research.Frontiers in human neuroscience · 2025Review
- [An emerging discipline: brain-computer interfaces medicine].Sheng wu yi xue gong cheng xue za zhi = Journal of biomedical engineering = Shengwu yixue gongchengxue zazhi · 2024Review
- [Ethical considerations for medical applications of implantable brain-computer interfaces].Sheng wu yi xue gong cheng xue za zhi = Journal of biomedical engineering = Shengwu yixue gongchengxue zazhi · 2024Article
- Update on How to Approach a Patient with Locked-In Syndrome and Their Communication Ability.Brain sciences · 2024Review
- Caregivers in implantable brain-computer interface research: a scoping review.Frontiers in human neuroscience · 2024Article
- Recent Progress in Long-Term Sleep Monitoring Technology.Biosensors · 2023Review
- Towards clinical application of implantable brain-computer interfaces for people with late-stage ALS: medical and ethical considerations.Journal of neurology · 2023Review
- Recommendations for promoting user agency in the design of speech neuroprostheses.Frontiers in human neuroscience · 2023Article
Corrections and comments
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Authors and funding
10 authors at 1 institution in 1 country.
Funding
Abstract
Implantable brain-computer interfaces (BCIs) promise to be a viable means to restore communication in individuals with locked-in syndrome (LIS). In 2016, we presented the world-first fully implantable BCI system that uses subdural electrocorticography electrodes to record brain signals and a subcutaneous amplifier to transmit the signals to the outside world, and that enabled an individual with LIS to communicate via a tablet computer by selecting icons in spelling software. For future clinical implementation of implantable communication-BCIs, however, much work is still needed, for example, to validate these systems in daily life settings with more participants, and to improve the speed of communication. We believe the design and execution of future studies on these and other topics may benefit from the experience we have gained. Therefore, based on relevant literature and our own experiences, we here provide an overview of procedures, as well as recommendations, for recruitment, screening, inclusion, imaging, hospital admission, implantation, training, and support of participants with LIS, for studies on daily life implementation of implantable communication-BCIs. With this article, we not only aim to inform the BCI community about important topics of concern, but also hope to contribute to improved methodological standardization of implantable BCI research.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.