Evidence map›Paper›PMID 36124891›Full record

ArticleThe Journal of international medical research2022

Long-term outcomes regarding arterial stiffness and carotid artery atherosclerosis in female patients with rapid eye movement obstructive sleep apnea.

Mayumi Suzuki, Ken Shimamoto, Fujio Tatsumi, Takao Tsuji, Natsumi Satoya, Yuji Inoue, Tetsuro Hoshino, Toshiaki Shiomi, Nobuhisa Hagiwara

Open access · goldAbstract read
In one paragraph

Article in The Journal of international medical research, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.5field-weighted citation impact, top 37% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 5 citations in OpenAlex.

  1. Sleep apnea in REM sleep as an amplifier of vascular contributions to Alzheimer's disease.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2026
    Review
  2. Article
  3. REM obstructive sleep apnea: prevalence and clinical associations in a high-altitude population.Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine · 2025
    Article
  4. REM-related obstructive sleep apnea: is it still an enigma or do we even care?Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine · 2025
    Article
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 1 country.

Mayumi SuzukiDivision of Comprehensive Sleep Medicine, Tokyo Women's Medical University Hospital (TWMU), Tokyo, Japan.ORCID 0000-0003-0655-4760
Ken ShimamotoDepartment of General Medicine, TWMU, Tokyo, Japan.
Fujio TatsumiInstitute of Geriatrics, TWMU, Tokyo, Japan.
Takao TsujiInstitute of Geriatrics, TWMU, Tokyo, Japan.
Natsumi SatoyaCentral Clinical Laboratory, TWMU, Tokyo, Japan.
Yuji InoueCentral Clinical Laboratory, TWMU, Tokyo, Japan.
Tetsuro HoshinoDepartment of Sleep Medicine, Graduate School of Biomedical and Health Sciences, Hiroshima University, Hiroshima, Japan.
Toshiaki ShiomiDepartment of Sleep Medicine, Graduate School of Biomedical and Health Sciences, Hiroshima University, Hiroshima, Japan.
Nobuhisa HagiwaraDivision of Comprehensive Sleep Medicine, Tokyo Women's Medical University Hospital (TWMU), Tokyo, Japan.
Hiroshima University · JPThe University of Tokyo · JPTokyo Women's Medical University Hospital · JPTokyo Women's Medical University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveRapid eye movement (REM) obstructive sleep apnea (OSA) is associated with the risk of cardiovascular events. Arterial stiffness and carotid artery intima-media thickness (IMT) predict these events, but few relevant studies have been conducted. We compared long-term changes in arterial stiffness and IMT between patients with REM OSA and non-REM (NREM) OSA receiving continuous positive airway pressure (CPAP) or oral appliance (OA) therapy.

methodsNewly diagnosed female patients with OSA received CPAP (n = 6) or OA (n = 7). Pulse wave velocity (PWV) and carotid artery ultrasound were performed before and 60 months after treatment.

resultsThere were no differences in baseline characteristics (mean age: 56.0 vs. 61.3 years; mean body mass index: 22.6 vs. 21.7 kg/m

conclusionArterial stiffness and glucose metabolism are deteriorated in patients with REM OSA compared with these parameters in patients with non-REM OSA after CPAP or OA treatment.

Indexed as

AtherosclerosisCarotid Artery DiseasesSleep Apnea, ObstructiveVascular StiffnessCarotid Artery, CommonCarotid Intima-Media ThicknessFemaleGlucoseHumansMiddle AgedPolysomnographyPulse Wave AnalysisSleep, REMGlucosearterial stiffnesscardiovascular eventglucose metabolismintima-media thicknessobstructive sleep apneaRapid eye movement

Identifiers

PMID36124891
PMCPMC9500274
OpenAlexW4296783497

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.