Evidence map›Paper›PMID 36124649›Full record

ArticleTransfusion medicine (Oxford, England)2022

Pathogen inactivation treatment of triple-dose apheresis platelets with amotosalen and ultraviolet a light.

Laura Infanti, Vildana Pehlic, Sandra Mitrovic, Andreas Holbro, Silke Andresen, Jean-Marc Payrat, Jin-Sying Lin, Andreas Buser

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Transfusion medicine (Oxford, England), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Laura InfantiRegional Blood Transfusion Service, Swiss Red Cross, Division of Hematology, University Hospital, Basel, Switzerland.ORCID https://orcid.org/0000-0001-7241-426X
Vildana PehlicRegional Blood Transfusion Service, Swiss Red Cross, Division of Hematology, University Hospital, Basel, Switzerland.
Sandra MitrovicClinical Chemistry, Department of Laboratory Medicine, University Hospital Basel, Basel, Switzerland.
Andreas HolbroRegional Blood Transfusion Service, Swiss Red Cross, Division of Hematology, University Hospital, Basel, Switzerland.
Silke AndresenCerus Europe B.V., Amersfoort, The Netherlands.
Jean-Marc PayratCerus Europe B.V., Amersfoort, The Netherlands.
Jin-Sying LinCerus Corporation, Concord, California, USA.
Andreas BuserRegional Blood Transfusion Service, Swiss Red Cross, Division of Hematology, University Hospital, Basel, Switzerland.

Funding

Cerus Corporation
6 · The paper itself

Abstract

backgroundA triple storage (TS) set allows for pathogen inactivation (PI) treatment of triple-dose apheresis platelet products with amotosalen + UVA. We evaluated the quality and metabolic parameters of platelet concentrates (PCs) pathogen inactivated and stored for 7 days. MATERIALS AND

methodsTwelve triple-dose products collected with two different apheresis platforms were treated with amotosalen+UVA. Products were split into three single-dose units. Testing was made pretreatment, after splitting, at days 5 and 7 of storage.

resultsSingle-dose PI PCs had a mean platelet content of 2.89 ± 0.35 x 10

conclusionTriple-dose PCs processed with the TS sets fulfilled the quality requirements and displayed metabolic changes of expected extent during 7-day storage.

Indexed as

Blood Component RemovalFurocoumarinsBlood PlateletsBlood PreservationHumansLactic AcidUltraviolet RaysamotosalenFurocoumarinsLactic Acidpathogen inactivationtriple-dose apheresis platelet components

Identifiers

PMID36124649
PMCPMC10087429

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.