Evidence map›Paper›PMID 36124646›Full record

ReviewCell transplantation

Designing Olfactory Ensheathing Cell Transplantation Therapies: Influence of Cell Microenvironment.

Mariyam Murtaza, Lipsa Mohanty, Jenny A K Ekberg, James A St John

Open access · goldAbstract readReview
In one paragraph

Review in Cell transplantation. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
1.2field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 12 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Mariyam MurtazaGriffith Institute for Drug Discovery, Griffith University, Brisbane, QLD, Australia.ORCID 0000-0001-7087-3809
Lipsa MohantyGriffith Institute for Drug Discovery, Griffith University, Brisbane, QLD, Australia.
Jenny A K EkbergGriffith Institute for Drug Discovery, Griffith University, Brisbane, QLD, Australia.ORCID 0000-0001-5151-4966
James A St JohnGriffith Institute for Drug Discovery, Griffith University, Brisbane, QLD, Australia.ORCID 0000-0001-7536-3381
Griffith University · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Olfactory ensheathing cell (OEC) transplantation is emerging as a promising treatment option for injuries of the nervous system. OECs can be obtained relatively easily from nasal biopsies, and exhibit several properties such as secretion of trophic factors, and phagocytosis of debris that facilitate neural regeneration and repair. But a major limitation of OEC-based cell therapies is the poor survival of transplanted cells which subsequently limit their therapeutic efficacy. There is an unmet need for approaches that enable the

Indexed as

NeurogliaOlfactory BulbCell TransplantationCellular MicroenvironmentOxygenOxygencell transplantationmicroenvironmentneural repairOECsstimulation

Identifiers

PMID36124646
PMCPMC9490465
OpenAlexW4296505075

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.