Evidence map›Paper›PMID 36124434›Full record

ArticleClinical transplantation2022

Utility of geriatric assessments in evaluation of older adults for kidney transplantation.

Kellie H Campbell, Daniel J Ahn, Frances Enger, Lindsay Zasadzinski, Jacob Tanumihardjo, Yolanda Becker, Michelle Josephson, Milda R Saunders

Open access · hybridAbstract read
In one paragraph

Article in Clinical transplantation, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 2 pooled it
3.1field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 2 syntheses or guidelines pooled it, 12 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Observational
  4. Article
  5. Review
  6. Review
  7. Article
  8. Old Age and Frailty in Deceased Organ Transplantation and Allocation-A Plea for Geriatric Assessment and Prehabilitation.Transplant international : official journal of the European Society for Organ Transplantation · 2023
    Article
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Kellie H CampbellGeriatrics and Extended Care, Edward J. Hines, Jr. Veterans Affairs Hospital, Chicago, Illinois, USA.
Daniel J AhnThe University of Chicago Pritzker School of Medicine, Chicago, Illinois, USA.
Frances EngerSection of General Internal Medicine, Department of Medicine, University of Chicago Medical Center, Chicago, Illinois, USA.
Lindsay ZasadzinskiSection of General Internal Medicine, Department of Medicine, University of Chicago Medical Center, Chicago, Illinois, USA.ORCID 0000-0001-7718-0933
Jacob TanumihardjoSection of General Internal Medicine, Department of Medicine, University of Chicago Medical Center, Chicago, Illinois, USA.
Yolanda BeckerSection of Transplant Surgery, Department of Surgery, University of Chicago Medical Center, Chicago, Illinois, USA.
Michelle JosephsonSection of Nephrology, Department of Medicine, University of Chicago Medical Center, Chicago, Illinois, USA.
Milda R SaundersSection of General Internal Medicine, Department of Medicine, University of Chicago Medical Center, Chicago, Illinois, USA.ORCID 0000-0002-9276-2066
University of Chicago Medical Center · USEdward Hines, Jr. VA Hospital · USUniversity of Chicago · US

Funding

Intensive Patient Referral and Education Program prior to Renal Replacement Therapy (iPREP RRT)R01DK124597 · NIDDK · UNIVERSITY OF CHICAGO · PI SAUNDERS, MILDA RENNE · 2020 to 2023
$1.3M
NIDDK NIH HHS R01 DK124597NIDDK NIH HHS R01DK124597NIDDK NIH HHS R21DK124597
6 · The paper itself

Abstract

backgroundWhile kidney transplantation has favorable outcomes in patients aged 65 years and older, many are not referred for evaluation despite having no contraindications. We wanted to determine whether incorporating geriatrics and geriatric assessments (GA), as part of kidney transplant evaluation at the University of Chicago Medicine, would help identify suitable candidates and improve transplantation outcomes among older adults.

methodsBetween 2012 and 2016, as part of their multi-disciplinary transplant evaluation, 171 patients underwent an initial GA with the study geriatrician, who rated them on a five-point scale from "poor" to "excellent," and presented their cases to multidisciplinary transplant review meetings. Patients were followed until June 1st, 2021. Predictor variables included geriatric recommendation, clinical characteristics, and demographics. Outcomes of interest were mortality, receipt of transplant, and waitlist placement.

resultsCompared to patients rated "poor," "marginal," or "fair," we found that patients that the geriatrician recommended as "good" or "excellent" were more likely to be waitlisted and receive a transplant. Favorably rated patients were also less likely to be removed from the waitlist due to becoming medically unfit, meaning worsening medical morbidity, frailty, and cognitive status.

conclusionIncluding geriatricians to perform GAs as part of the transplant evaluation process can help identify suitable elderly candidates.

Indexed as

FrailtyKidney TransplantationAgedGeriatric AssessmentHumansolder adultstransplant accesstransplant evaluation

Identifiers

PMID36124434
PMCPMC10078529
OpenAlexW4296482471

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.