Evidence map›Paper›PMID 36124416›Full record

ArticleJournal of cardiac surgery2022

The impact of race on utilization of durable left ventricular assist device therapy in patients with advanced heart failure.

Mandisa-Maia Jones, Lisa M McElroy, Manal Mirreh, Matthew Fuller, Rebecca Schroeder, Kamrouz Ghadimi, Adam DeVore, Chetan B Patel, Eric Black-Maier, Raquel Bartz and 1 more

Open access · greenAbstract read
In one paragraph

Article in Journal of cardiac surgery, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.4field-weighted citation impact, top 45% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 5 institutions in 1 country.

Mandisa-Maia JonesDepartment of Anesthesiology, Division of Cardiothoracic and Critical Care Medicine, Weill Cornell Medicine, New York, New York, USA.ORCID http://orcid.org/0000-0001-5574-4355
Lisa M McElroyDepartment of Surgery, Division of Abdominal Transplant Surgery, Duke University Medical Center, Durham, North Carolina, USA.
Manal MirrehDepartment of Anesthesiology, Division of Pediatric Anesthesiology, University of Michigan Hospital, Ann Arbor, Michigan, USA.
Matthew FullerDepartment of Anesthesiology, Division of Cardiothoracic and Critical Care Medicine, Duke University Medical Center, Durham, North Carolina, USA.
Rebecca SchroederDepartment of Anesthesiology, Duke University School of Medicine, VAMC, Durham, North Carolina, USA.
Kamrouz GhadimiDepartment of Anesthesiology, Division of Cardiothoracic and Critical Care Medicine, Duke University Medical Center, Durham, North Carolina, USA.
Adam DeVoreDepartment of Medicine, Duke University Medical Center, Durham, North Carolina, USA.
Chetan B PatelDepartment of Medicine, Duke University Medical Center, Durham, North Carolina, USA.
Eric Black-MaierDepartment of Medicine, Duke University Medical Center, Durham, North Carolina, USA.
Raquel BartzDepartment of Anesthesiology, Brigham and Women's Hospital, Boston, Massachusetts, USA.
Kevin ThomasDepartment of Medicine, Duke University Medical Center, Durham, North Carolina, USA.
Duke Medical Center · USBrigham and Women's Hospital · USCornell University · USDuke University · USUniversity of Michigan · US

Funding

Research Project 3U54MD012530 · NIMHD · DUKE UNIVERSITY · PI JOHNSON, KIMBERLY S. · 2017 to 2022
$8.8M
NIMHD NIH HHS U54 MD012530
6 · The paper itself

Abstract

backgroundHeart failure affects >6 million people in the United States alone and is most prevalent in Black patients who suffer the highest mortality risk. Yet prior studies have suggested that Black patients are less likely to receive advanced heart failure therapy. We hypothesized that Black patients would have decreased rates of durable left ventricular assist device (LVAD) implantation within our expansive heart failure program.

methodsA retrospective single-center cohort study was conducted at a single high-volume academic medical center. Patients between 18 and 85 years admitted with a diagnosis of cardiogenic shock or congestive heart failure between 1, 2013 and 12, 2017 with a left ventricular ejection fraction < 30% and inotropic dependence or need for mechanical circulatory support were included. Patients with contraindications to durable LVAD were excluded. An adjusted logistic regression model for durable LVAD implantation within 90 days of the index admission was used to determine the effect of race on durable LVAD implantation.

resultsAmong the 702 study patients (60.9% White, 34.1% Black), durable LVAD implantation was performed within 90 days of the index admission in 183 (26%) of the cohort. After multivariate analysis, Black patients were not found to have a statistically significant difference in durable LVAD implantation rates compared to White patients in our study (OR: 0.68 [95% confidence interval: 0.45-1.04; p: .074]).

conclusionsBlack patients in our study did not have a statistically significant difference in the rate of durable LVAD implantation compared with White patients after adjustments were made for age, sex, socioeconomic, and clinical covariates. Larger prospective studies are needed to validate these findings.

Indexed as

Heart-Assist DevicesHeart FailureCohort StudiesHumansRetrospective StudiesStroke VolumeTreatment OutcomeUnited StatesVentricular Function, Leftgenderheart failureleft ventricular assist devicerace

Identifiers

PMID36124416
PMCPMC11193413
OpenAlexW4296781806

What OpenQuestion holds

Textmetadata
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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.