Evidence map›Paper›PMID 36124298›Full record

ArticleRisk management and healthcare policy2022

The Impact of COVID-19 Pandemic on Ischemic Stroke Patients in a Comprehensive Hospital.

Yimin Chen, Thanh N Nguyen, James E Siegler, Mohammad Mofatteh, Jack Wellington, Rongshen Yang, Lihong Zeng, Jiale Wu, Xi Sun, Daiyu Liang and 5 more

Open access · goldAbstract read
In one paragraph

Article in Risk management and healthcare policy, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
1.3field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 12 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 8 institutions in 3 countries.

Yimin ChenDepartment of Neurology and Advanced National Stroke Center, Foshan Sanshui District People's Hospital, Foshan, People's Republic of China.ORCID 0000-0002-1805-6665
Thanh N NguyenDepartment of Neurology, Radiology, Boston University School of Medicine, Boston, MA, USA.
James E SieglerCooper Neurological Institute, Cooper University Hospital, Camden, NJ, USA.
Mohammad MofattehSchool of Medicine, Dentistry and Biomedical Sciences, Queen's University Belfast, Belfast, UK.ORCID 0000-0002-2458-0447
Jack WellingtonSchool of Medicine, Cardiff University, Cardiff, UK.
Rongshen YangMedical Intern of Neurology Department, Foshan Sanshui District People's Hospital, Foshan, People's Republic of China.
Lihong ZengDepartment of Neurology and Advanced National Stroke Center, Foshan Sanshui District People's Hospital, Foshan, People's Republic of China.
Jiale WuMedical Intern of Neurology Department, Foshan Sanshui District People's Hospital, Foshan, People's Republic of China.
Xi SunMedical Intern of Neurology Department, Foshan Sanshui District People's Hospital, Foshan, People's Republic of China.
Daiyu LiangMedical Intern of Neurology Department, Foshan Sanshui District People's Hospital, Foshan, People's Republic of China.
Qiubi TangChronic Disease Department, The Affiliated Brain Hospital of Guangzhou Medical University, Guangzhou, People's Republic of China.ORCID 0000-0002-9481-7841
Sijie ChenMedical Intern of Neurology Department, Foshan Sanshui District People's Hospital, Foshan, People's Republic of China.
Xisheng HuangMedical Intern of Neurology Department, Foshan Sanshui District People's Hospital, Foshan, People's Republic of China.
Shuiquan YangDepartment of Neurology and Advanced National Stroke Center, Foshan Sanshui District People's Hospital, Foshan, People's Republic of China.
Xuxing LiaoDean Office and Advanced National Stroke Center, Foshan Sanshui District People's Hospital, Foshan, People's Republic of China.
Shaoguan University · CNFoshan Second People's Hospital · CNBoston University · USCardiff University · GBCooper University Hospital · USFirst People's Hospital of Foshan · CNGuangzhou Medical University · CNQueen's University Belfast · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Purpose: This study aimed to investigate the impact of characteristic ischemic stroke and outcomes during the first COVID-19 pandemic lockdown. Patients and Methods: A retrospective, observational cohort study of a comprehensive tertiary stroke center was conducted. Patients with ischemic stroke were divided into pre-COVID-19 lockdown (11/1/2019 to 1/30/2020) and COVID-19 lockdown (1/31/2020 to 4/30/2020) period groups. Patient data on stroke admission, thrombolysis, endovascular treatment, and 3-month routine follow-up were recorded. Data analysis was performed using SPSS according to values following a Gaussian distribution. Results: The pre-COVID-19 lockdown period group comprised 230 patients compared to 215 patients in the COVID-19 lockdown period group. Atrial fibrillation was more predominant in the COVID-19 lockdown period group (11.68% vs 5.65%, p=0.02) alongside patients who were currently smoking (38.8% vs 28.7%, p=0.02) and drinking alcohol (30.37% vs 20.00%, p=0.012) compared with that of the pre-COVID-19 lockdown period group. For patients receiving thrombolysis, the median door-to-CT time was longer in the COVID-19 lockdown period group (17.0 min (13.0, 24.0) vs 12.0 min (8.0, 17.3), p=0.012), median door to needle time was 48.0 minutes (35.5, 73.0) vs 43.5 minutes (38.0, 53.3), p=0.50, compared with that of the pre-COVID-19 lockdown period group. There were no differences for patients receiving mechanical thrombectomy. The median length of hospitalization (IQR) was no different. Discharge mRS scores (IQR) were higher in the COVID-19 lockdown period group (1.0 (1.0, 3.0) vs 1.0 (1.0, 2.0), p=0.022). Compared with the pre-COVID-19 lockdown period, hospitalization cost (Chinese Yuan) in the COVID-19 period group was higher (13,445.7 (11,009.7, 20,030.5) vs 10,799.2 (8692.4, 16,381.7), p=0.000). There was no difference observed in 3-month mRS scores. Conclusion: Patients presenting with ischemic stroke during the COVID-19 pandemic lockdown period had longer median door-to-CT time and higher hospitalization costs. There were no significant differences in 3-month outcomes. Multidisciplinary collaboration and continuous workflow optimization may maintain stroke care during the COVID-19 pandemic lockdown.

Indexed as

COVID-19 pandemichospitalization costischemic strokethrombectomythrombolysis

Identifiers

PMID36124298
PMCPMC9482438
OpenAlexW4297820449

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.