Evidence map›Paper›PMID 36124200›Full record

ReviewInternational journal of ophthalmology2022

Ocular stem cells: a narrative review of current clinical trials.

Konstadinos Sotiropulos, Dimitrios Kourkoutas, Diamantis Almaliotis, Katherine Ploumidou, Vasileios Karampatakis

Abstract readReview
In one paragraph

Review in International journal of ophthalmology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Review
  2. Utilization of Stem Cells in Medicine: A Narrative Review.International journal of molecular sciences · 2025
    Review
  3. Review
  4. Seeing the Future: A Review of Ocular Therapy.Bioengineering (Basel, Switzerland) · 2024
    Review
  5. Review
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Konstadinos SotiropulosDepartment of Ophthalmology, 417 Army Shared Fund Hospital, Athens11521, Greece.
Dimitrios KourkoutasDepartment of Ophthalmology, 401 Army General Hospital of Athens, Athens11525, Greece.
Diamantis AlmaliotisLaboratory of Experimental Ophthalmology, School of Medicine, Aristotle University of Thessaloniki, Thessaloniki 54124, Greece.
Katherine PloumidouDepartment of Otolaryngology, Children's Hospital "Aglaia Kyriakou", Athens 11527, Greece.
Vasileios KarampatakisLaboratory of Experimental Ophthalmology, School of Medicine, Aristotle University of Thessaloniki, Thessaloniki 54124, Greece.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Stem cells are undifferentiated cells showcasing a remarkable capacity of self-replenishing and differentiating into mature cells. Their ability to proliferate connotes that a designated stem cell source is capable of generating an unrestricted number of mature cells. The ever-increasing comprehension of position, activity, and function of ocular stem cells has led to rapid progress and incessant improvement of possible procedures and therapies. A narrative review was conducted to summarize the current evidence on clinical trials and respective literature, regarding current evolution in the field of ocular regenerative medicine. We tried to ascertain the safety of experimental and clinical procedures, their effectiveness, and the ethical repercussion of their use.

Indexed as

cell-based therapieshESC-derived retinal pigment epitheliumhuman induced pluripotent stem cellslimbal stem cellsolfactory mucosa mesenchymal stem cellsstem cells

Identifiers

PMID36124200
PMCPMC9453397

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.