Evidence map›Paper›PMID 36124131›Full record

ArticlePeerJ2022

5-Methylindole kills various bacterial pathogens and potentiates aminoglycoside against methicillin-resistant

Zhongyan Li, Fengqi Sun, Xinmiao Fu, Yajuan Chen

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in PeerJ, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.4field-weighted citation impact, top 39% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 4 citations in OpenAlex.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Zhongyan Li *Fujian Normal University, Fuzhou, Fujian, China.
Fengqi Sun *Fujian Normal University, Fuzhou, Fujian, China.
Xinmiao FuFujian Normal University, Fuzhou, Fujian, China.ORCID 0000-0003-3361-6904
Yajuan ChenFujian Normal University, Fuzhou, Fujian, China.ORCID 0000-0002-0640-7608
Fujian Normal University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Antibiotic resistance of bacterial pathogens has become a severe threat to human health. To counteract antibiotic resistance, it is of significance to discover new antibiotics and also improve the efficacy of existing antibiotics. Here we show that 5-methylindole, a derivative of the interspecies signaling molecule indole, is able to directly kill various Gram-positive pathogens (

Indexed as

Methicillin-Resistant Staphylococcus aureusAminoglycosidesAnti-Bacterial AgentsBacteriaEscherichia coliHumansIndolesProtein Synthesis InhibitorsStaphylococcus aureus5-methylindoleAminoglycosidesAnti-Bacterial AgentsIndolesProtein Synthesis Inhibitors5-MethylindoleAminoglycosideAntibiotic resistanceAntibiotic toleranceGram-positive bacteriaIndoleMRSAPersisterStaphylococcus aureus

Identifiers

PMID36124131
PMCPMC9482361
OpenAlexW4295798536

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.