Evidence map›Paper›PMID 36124042›Full record

ReviewNature reviews. Materials2022

Mucosa-interfacing electronics.

Kewang Nan, Vivian R Feig, Binbin Ying, Julia G Howarth, Ziliang Kang, Yiyuan Yang, Giovanni Traverso

Abstract readReview
In one paragraph

Review in Nature reviews. Materials, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers.

0numbers the graph read from it
0cells of the map it votes in
29citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

29 citing papers in PubMed.

  1. Gastric slow-wave morphology in health and disease.Digestive diseases and sciences · 2026
    Article
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  5. Review
  6. Review
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  13. Offbeat drug-delivery tactics.Nature biomedical engineering · 2024
    Article
  14. Article
  15. Article
  16. Article
  17. Next generation of gastrointestinal electrophysiology devices.Nature reviews. Gastroenterology & hepatology · 2024
    Article
  18. Motion artefact management for soft bioelectronics.Nature reviews bioengineering · 2024
    Article
  19. Challenges in IBD Research 2024: Novel Technologies.Inflammatory bowel diseases · 2024
    Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Kewang Nan *Department of Mechanical Engineering, Massachusetts Institute of Technology, Cambridge, MA USA.
Vivian R Feig *Division of Gastroenterology, Hepatology and Endoscopy, Brigham and Women's Hospital, Harvard Medical School, Boston, MA USA.
Binbin Ying *Department of Mechanical Engineering, Massachusetts Institute of Technology, Cambridge, MA USA.
Julia G HowarthDepartment of Mechanical Engineering, Massachusetts Institute of Technology, Cambridge, MA USA.
Ziliang KangDepartment of Mechanical Engineering, Massachusetts Institute of Technology, Cambridge, MA USA.ORCID 0000-0002-7010-6308
Yiyuan YangDepartment of Mechanical Engineering, Massachusetts Institute of Technology, Cambridge, MA USA.
Giovanni TraversoDepartment of Mechanical Engineering, Massachusetts Institute of Technology, Cambridge, MA USA.ORCID 0000-0001-7851-4077

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The surface mucosa that lines many of our organs houses myriad biometric signals and, therefore, has great potential as a sensor-tissue interface for high-fidelity and long-term biosensing. However, progress is still nascent for mucosa-interfacing electronics owing to challenges with establishing robust sensor-tissue interfaces; device localization, retention and removal; and power and data transfer. This is in sharp contrast to the rapidly advancing field of skin-interfacing electronics, which are replacing traditional hospital visits with minimally invasive, real-time, continuous and untethered biosensing. This Review aims to bridge the gap between skin-interfacing electronics and mucosa-interfacing electronics systems through a comparison of the properties and functions of the skin and internal mucosal surfaces. The major physiological signals accessible through mucosa-lined organs are surveyed and design considerations for the next generation of mucosa-interfacing electronics are outlined based on state-of-the-art developments in bio-integrated electronics. With this Review, we aim to inspire hardware solutions that can serve as a foundation for developing personalized biosensing from the mucosa, a relatively uncharted field with great scientific and clinical potential.

Indexed as

Biomedical engineeringSensors and biosensors

Identifiers

PMID36124042
PMCPMC9472746

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.