Evidence map›Paper›PMID 36123789›Full record

ArticleInternational journal of immunopathology and pharmacology

Multiple sites of thrombosis without thrombocytopenia after a second dose of Pfizer-BioNTech COVID-19 vaccine.

Roberto Scendoni, Cristina Petrelli, Mauro Giustozzi, Francesco O Logullo

Open access · goldAbstract readCase Reports
In one paragraph

Article in International journal of immunopathology and pharmacology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.7field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Roberto ScendoniLegal Medicine Unit, 125694ASUR Marche, Macerata, Italy.ORCID 0000-0003-1910-2405
Cristina PetrelliNeurological Unit, 125694ASUR Marche, Macerata, Italy.
Mauro GiustozziEmergency Department, 125694ASUR Marche, Macerata, Italy.
Francesco O LogulloNeurological Unit, 125694ASUR Marche, Macerata, Italy.
University of Macerata · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In the current international scientific panorama, rare cases of venous thrombotic complications following mRNA vaccine administration have been reported, consisting mainly of cerebral sinus thromboses and acute venous thromboembolism. The present paper describes the case of a 75-year-old woman in good health who developed cerebral venous thrombosis, deep venous thrombosis, and bilateral pulmonary emboli after receiving a second dose of Pfizer-BioNTech COVID-19 vaccine. A series of laboratory tests performed during hospitalization yielded interesting results, allowing us to exclude thrombophilic risk factors and to certify the absence of thrombocytopenia in the patient. Although COVID-19 vaccination is the most important tool in stopping the pandemic, pharmacovigilance is crucial for detecting potential multisystem thrombotic events, even for mRNA vaccines.

Indexed as

BNT162 VaccineCOVID-19ThrombosisAgedFemaleHumansThrombocytopeniaBNT162 Vaccinecomputed tomographyCOVID-19 infectionPfizer-BioNTech vaccinethrombocytopeniathromboembolismvenous thrombosis

Identifiers

PMID36123789
PMCPMC9486676
OpenAlexW4296507963

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.