Evidence map›Paper›PMID 36123776›Full record

ReviewJournal of child psychology and psychiatry, and allied disciplines2023

Annual Research Review: Developmental pathways linking early behavioral inhibition to later anxiety.

Nathan A Fox, Selin Zeytinoglu, Emilio A Valadez, George A Buzzell, Santiago Morales, Heather A Henderson

Abstract readReview
In one paragraph

Review in Journal of child psychology and psychiatry, and allied disciplines, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 40 papers.

0numbers the graph read from it
0cells of the map it votes in
40citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

40 citing papers in PubMed.

  1. Trial
  2. Review
  3. Review
  4. Parent-Child Neural Dynamics during a Stressful Task: Probing Associations with Temperament and Anxiety.Clinical psychological science : a journal of the Association for Psychological Science · 2026
    Article
  5. Article
  6. Neural correlates of child temperament: The role of brain network connectivity in psychopathology risk.Journal of child psychology and psychiatry, and allied disciplines · 2026
    Article
  7. Peer and familial influences on the association between behavioral inhibition and trajectories of social anxiety symptoms across adolescence.Journal of research on adolescence : the official journal of the Society for Research on Adolescence · 2026
    Article
  8. Article
  9. Sensory hyperacusis as a predictor of anxiety in adolescence.Journal of child psychology and psychiatry, and allied disciplines · 2026
    Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
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  18. Generational Trends in Children's Shyness: Does COVID-19 Matter?Child psychiatry and human development · 2025
    Article
  19. Article
  20. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

6 authors.

Nathan A FoxDepartment of Human Development and Quantitative Methodology, University of Maryland, College Park, MD, USA.ORCID 0000-0003-4452-4503
Selin ZeytinogluDepartment of Human Development and Quantitative Methodology, University of Maryland, College Park, MD, USA.ORCID 0000-0002-2736-4061
Emilio A ValadezDepartment of Human Development and Quantitative Methodology, University of Maryland, College Park, MD, USA.ORCID 0000-0002-6614-8628
George A BuzzellDepartment of Psychology, Florida International University, Miami, FL, USA.ORCID 0000-0003-3324-3183
Santiago MoralesDepartment of Psychology, University of Southern California, Los Angeles, CA, USA.ORCID 0000-0002-9850-042X
Heather A HendersonDepartment of Psychology, University of Waterloo, Waterloo, ON, Canada.ORCID 0000-0002-1668-4203

Funding

Trajectories of Behavioral Inibition and Risk for AnxietyU01MH093349 · NIMH · UNIV OF MARYLAND, COLLEGE PARK · PI FOX, NATHAN A · 2011 to 2020
$6.6M
Mother-Child Dynamics in the Transmission of Social Anxiety: The Roles of Maternal Verbal Communication and Child AttentionF32MH127869 · NIMH · UNIV OF MARYLAND, COLLEGE PARK · PI ZEYTINOGLU, SELIN · 2021 to 2024
$240k
NIMH NIH HHS F32 MH127869NIMH NIH HHS U01 MH093349
6 · The paper itself

Abstract

Behavioral Inhibition is a temperament identified in the first years of life that enhances the risk for development of anxiety during late childhood and adolescence. Amongst children characterized with this temperament, only around 40 percent go on to develop anxiety disorders, meaning that more than half of these children do not. Over the past 20 years, research has documented within-child and socio-contextual factors that support differing developmental pathways. This review provides a historical perspective on the research documenting the origins of this temperament, its biological correlates, and the factors that enhance or mitigate risk for development of anxiety. We review as well, research findings from two longitudinal cohorts that have identified moderators of behavioral inhibition in understanding pathways to anxiety. Research on these moderators has led us to develop the Detection and Dual Control (DDC) framework to understand differing developmental trajectories among behaviorally inhibited children. In this review, we use this framework to explain why and how specific cognitive and socio-contextual factors influence differential pathways to anxiety versus resilience.

Indexed as

AnxietyAnxiety DisordersAdolescentChildHumansInhibition, PsychologicalTemperamentanxietychild developmentdevelopmental psychopathologyelectroencephalographyTemperament

Identifiers

PMID36123776
PMCPMC10690832

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.