Evidence map›Paper›PMID 36123773›Full record

ArticleChronic respiratory disease

Incidence, prevalence and regional distribution of systemic sclerosis and related interstitial lung Disease: A nationwide retrospective cohort study.

Malene Knarborg, Charlotte Hyldgaard, Elisabeth Bendstrup, Jesper R Davidsen, Anders Løkke, Saher B Shaker, Ole Hilberg

Open access · goldAbstract read
In one paragraph

Article in Chronic respiratory disease. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed, 3 pooled it
2.2field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 3 syntheses or guidelines pooled it, 15 citations in OpenAlex.

  1. Pooled it
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  10. Pathogenesis of interstitial lung disease in systemic sclerosis.Rheumatology and immunology research · 2024
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 1 country.

Malene KnarborgDepartment of Medicine, 371420Lillebaelt Hospital, Vejle, Denmark.ORCID 0000-0003-2398-9096
Charlotte HyldgaardDiagnostic Centre, University Research Clinic for Innovative Patient Pathways, 53179Silkeborg Regional Hospital, Silkeborg, Denmark.ORCID 0000-0002-6353-8671
Elisabeth BendstrupCenter for Rare Lung Diseases, Department of Respiratory Diseases and Allergy, 11297Aarhus University Hospital, Aarhus, Denmark.
Jesper R DavidsenSouth Danish Center for Interstitial Lung Diseases (SCILS), Department of Respiratory Medicine, 11286Odense University Hospital, Odense, Denmark.
Anders LøkkeDepartment of Medicine, 371420Lillebaelt Hospital, Vejle, Denmark.
Saher B ShakerDepartment of Respiratory Medicine, 53147Herlev and Gentofte University Hospital, Copenhagen, Denmark.
Ole HilbergDepartment of Medicine, 371420Lillebaelt Hospital, Vejle, Denmark.
University of Southern Denmark · DKAarhus University · DKGentofte Hospital · DKRegionshospitalet Silkeborg · DK

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo investigate incidence and prevalence of Systemic Sclerosis (SSc) and association with interstitial lung disease (SSc-ILD) in a nationwide population-based study.

methodsPatients with an incident diagnosis of SSc in 2000-2016 were identified in the Danish National Patient Registry and categorised based on diagnosis of ILD. Incidence- and prevalence proportions were calculated based on the annual population estimates. A cox proportional hazards model was used to evaluate the association between age, sex, region and marital status and presence of ILD.

resultsIn total, 1869 patients with SSc were identified; 275 patients (14.7%) had SSc-ILD. The majority of patients were females (75.5%). The percentage of males was higher in SSc-ILD than in SSc alone (30.9% and 23.4%,

conclusionThe prevalence of SSc increased during the study period, while the incidence remained stable. The prevalence of SSc-ILD was 14.7% and thus less frequent than expected. Male sex and age between 41 and 50 years were associated with ILD.

Indexed as

Lung Diseases, InterstitialScleroderma, SystemicAdultFemaleHumansIncidenceMaleMiddle AgedPrevalenceRetrospective Studiesepidemiologygeographical distributionincidenceinterstitial lung diseaseprevalenceSystemic sclerosis

Identifiers

PMID36123773
PMCPMC9500307
OpenAlexW4296507825

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.