Evidence map›Paper›PMID 36123743›Full record

ArticleLipids in health and disease2022

Alcohol-dependent downregulation of apolipoprotein H exacerbates fatty liver and gut microbiota dysbiosis in mice.

Yaming Liu, Zhe Wu, Yong Zhang, Binbin Chen, Shuqi Yu, Wanyun Li, Jianlin Ren

Open access · goldAbstract read
In one paragraph

Article in Lipids in health and disease, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.2field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 10 citations in OpenAlex.

  1. Review
  2. Article
  3. Review
  4. HostFrontiers in microbiology · 2025
    Article
  5. Article
  6. Article
  7. Article
  8. Heliyon · 2023
    Article
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Yaming LiuDepartment of Gastroenterology and Hepatology, Xiamen University Zhongshan Hospital, Xiamen, 361001, Fujian Province, China.
Zhe WuDigestive Department, Peking University People's Hospital, Beijing, 100001, China.
Yong ZhangDepartment of Digestive Diseases, School of Medicine, Xiamen University, Xiamen, 361001, Fujian Province, China.
Binbin ChenDepartment of Digestive Diseases, School of Medicine, Xiamen University, Xiamen, 361001, Fujian Province, China.
Shuqi YuDepartment of Pathology, Xiamen University Zhongshan Hospital, Xiamen, 361001, Fujian Province, China.
Wanyun LiDepartment of Digestive Diseases, School of Medicine, Xiamen University, Xiamen, 361001, Fujian Province, China.
Jianlin RenDepartment of Gastroenterology and Hepatology, Xiamen University Zhongshan Hospital, Xiamen, 361001, Fujian Province, China. Ren.Jianlin@outlook.com.
Xiamen University · CNZhongshan Hospital of Xiamen University · CNPeking University People's Hospital · CN

Funding

Health and Young Backbone Talents Training Project of Fujian Provinc 2019-ZQNB-30National Natural Science Foundation of China 81900492
6 · The paper itself

Abstract

backgroundAlcohol-related liver disease (ALD) is a major chronic liver ailment caused by alcohol overconsumption and abuse. Apolipoprotein H (APOH) participates in lipid metabolism and might have a potential regulatory role in ALD. Therefore, this study aimed to explore the effects of ApoH on alcohol-induced liver injury and gut microbiota dysbiosis.

methodsApoH

resultsApoH

conclusionsAlcohol-downregulated ApoH expression, leading to the progress of fatty liver disease and gut microbiota dysbiosis.

Indexed as

AlcoholismFatty LiverGastrointestinal MicrobiomeLiver DiseasesAnimalsbeta 2-Glycoprotein IDown-RegulationDysbiosisEthanolMiceRNA, Ribosomal, 16Sbeta 2-Glycoprotein IEthanolRNA, Ribosomal, 16SAlcohol-related liver diseaseApolipoprotein HFatty liverGut microbiotaLipid metabolism

Identifiers

PMID36123743
PMCPMC9487114
OpenAlexW4296457250

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.