ArticleBMC complementary medicine and therapies2022
Ethnobotanical study of Hakka traditional medicine in Ganzhou, China and their antibacterial, antifungal, and cytotoxic assessments.
Article in BMC complementary medicine and therapies, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
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14 citing papers in PubMed.
- Bioassay-guided Isolation of Antibacterial Compounds from Ethanolic Extract of Alstonia scholaris (L.) R. Br. Leaves and Developmental Toxicity Evaluation in Zebrafish (Danio rerio) Embryos.Current microbiology · 2026Article
- Traditional wisdom unveiled: an ethnobotanical exploration of medicinal bath plants for postpartum and infant healthcare among the Hakka people in Guangdong, China.BMC complementary medicine and therapies · 2026Article
- Advances on Ethnobotanical, Phytochemical, and Preclinical Studies ofJournal of experimental pharmacology · 2026Review
- Antibacterial Activity, Phytochemical Composition, and Cytotoxicity Evaluation of Select Medicinal Plants from Bangladesh.Current microbiology · 2025Article
- Polyprenylated Acylphloroglucinols fromPharmaceuticals (Basel, Switzerland) · 2025Article
- Medicinal plants traded in Hakka communities of southeastern Guangxi, China.Journal of ethnobiology and ethnomedicine · 2025Article
- Article
- Investigation of phytochemical profiling and biological activities of methanol extract fromFrontiers in plant science · 2025Article
- Biofilm targeting with chitosan-based nanohydrogel containing Quercus infectoria G. Olivier extract against Streptococcus mutans: new formulations of a traditional natural product.BMC complementary medicine and therapies · 2024Article
- A field survey on the dietary use of traditional Chinese medicine in selected regions with the Cantonese, Hakka, and Teochew populations in Guangdong province, China.Food science & nutrition · 2024Article
- Chlorogenic acid inhibits macrophage PANoptosis induced by cefotaxime-resistant Escherichia coli.Archives of microbiology · 2024Article
- Utilization of the Shensheng-Piwen changed medicinal powder extracts combines metal-organic frameworks as an antibacterial agent.Frontiers in cellular and infection microbiology · 2024Article
- Review
- Metabolic profiling ofFrontiers in plant science · 2023Article
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8 authors.
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Abstract
backgroundTraditional herbs played a crucial role in the health care of the Hakka people. However, studies to identify these traditional herbs are few. Here we document and assess the potential of these plants for treating microbial infections. Many herbs used by the Hakka people could potentially be a novel medicinal resource.
methodsLocal herb markets were surveyed via semi-structured interviews, complemented by direct observations to obtain information on herbal usage. For each herb selected for this study, extracts in four different solvents were prepared, and tested for activity against 20 microorganisms, as well as cancerous and noncancerous cells. All data were subjected to cluster analysis to discover relationships among herbs, plant types, administration forms, solvents, microorganisms, cells, etc., with the aim to discern promising herbs for medicine.
resultsNinety-seven Hakka herbs in Ganzhou were documented from 93 plants in 62 families; most are used for bathing (97%), or as food, such as tea (32%), soup (12%), etc. Compared with the Chinese Pharmacopoeia and Chinese Materia Medica, 24 Hakka medicines use different plant parts, and 5 plants are recorded here for the first time as traditional medicines. The plant parts used were closely related with the life cycle: annual and perennial herbs were normally used as a whole plant, and woody plants as (tender) stem and leaf, indicating a trend to use the parts that are easily collected. Encouragingly, 311 extracts (94%) were active against one or more microorganisms. Most herbs were active against Gram-positive bacteria, such as Staphylococcus aureus (67%), Listeria innocua (64%), etc. Cytotoxicity was often observed against a tumor cell, but rarely against normal cells. Considering both antimicrobial activity and cytotoxicity, many herbs reported in this study show promise as medicine.
conclusionHakka people commonly use easily-collected plant parts (aerial parts or entire herb) as medicine. External use of decoctions dominated, and may help combating microbial infections. The results offer promising perspectives for further research since little phytopharmacology and phytochemistry has been published to date.
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