Evidence map›Paper›PMID 36123695›Full record

ArticleBiotechnology for biofuels and bioproducts2022

First report on Vitamin B

Luca Mastella, Vittorio G Senatore, Lorenzo Guzzetti, Martina Coppolino, Luca Campone, Massimo Labra, Tiziana Beltrani, Paola Branduardi

Open access · goldAbstract read
In one paragraph

Article in Biotechnology for biofuels and bioproducts, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.1field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 16 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Luca Mastella *Department of Biotechnology and Biosciences, University of Milano Bicocca, Piazza della Scienza,2, 20126, Milan, Italy.
Vittorio G Senatore *Department of Biotechnology and Biosciences, University of Milano Bicocca, Piazza della Scienza,2, 20126, Milan, Italy.
Lorenzo GuzzettiDepartment of Biotechnology and Biosciences, University of Milano Bicocca, Piazza della Scienza,2, 20126, Milan, Italy.
Martina CoppolinoDepartment of Biotechnology and Biosciences, University of Milano Bicocca, Piazza della Scienza,2, 20126, Milan, Italy.
Luca CamponeDepartment of Biotechnology and Biosciences, University of Milano Bicocca, Piazza della Scienza,2, 20126, Milan, Italy.
Massimo LabraDepartment of Biotechnology and Biosciences, University of Milano Bicocca, Piazza della Scienza,2, 20126, Milan, Italy.
Tiziana BeltraniLaboratory for Resources Valorization (RISE), Department for Sustainability, ENEA- Italian National Agency for New Technologies, Energy and Sustainable Economic Development, S. Maria di Galeria, Rome, Italy.
Paola BranduardiDepartment of Biotechnology and Biosciences, University of Milano Bicocca, Piazza della Scienza,2, 20126, Milan, Italy. paola.branduardi@unimib.it.
University of Milano-Bicocca · ITNational Agency for New Technologies, Energy and Sustainable Economic Development · IT

Funding

Accordo di collaborazione Regione Lombardia-ENEA Dgr 7792/2018Food Social Sensor Network FOODNET, 2016 - NAZ - 0143/A
6 · The paper itself

Abstract

backgroundThe demand for naturally derived products is continuously growing. Nutraceuticals such as pre- and post-biotics, antioxidants and vitamins are prominent examples in this scenario, but many of them are mainly produced by chemical synthesis. The global folate market is expected to register a CAGR of 5.3% from 2019 to 2024 and reach USD 1.02 billion by the end of 2024. Vitamin B

resultsGlucose and xylose are the main sugars released during the pretreatment and hydrolysis processes of several residual lignocellulosic biomasses (such as corn stover, wheat straw or bagasse). We optimized the growth conditions in minimal medium formulated with these sugars and investigated the key role of oxygenation and nitrogen source on folate production. Vitamin B

conclusionsFor the first time, the non-Saccharomyces yeast S. stipitis was used to produce folate. The results confirm its potential as a microbial cell factory for folate production, which can be also improved both by genetic engineering strategies and by fine-tuning the fermentation conditions and nutrient requirements.

Indexed as

5MTHFBiorefineryNutraceuticalsScheffersomyces stipitisTHF

Identifiers

PMID36123695
PMCPMC9487109
OpenAlexW4296370396

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.