ArticleBMC pediatrics2022
Risk factors and antibiotic sensitivity of aerobic bacteria in Chinese children with adenoid hypertrophy.
Article in BMC pediatrics, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
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Who cites it
6 citing papers in PubMed, 11 citations in OpenAlex.
- Oral versus intranasal probiotics for nasal microbiome modulation: a comparative review of route-dependent mechanisms and clinical implications.Folia microbiologica · 2026Review
- Comprehensive spatial profiling reveals transitional microbiome dynamics and microbial heterogeneity in pediatric adenoid hypertrophy.iMetaOmics · 2026Article
- Molecular and Drug Resistance Characteristics ofMicroorganisms · 2025Article
- Comparing the Microbiome of the Adenoids in Children with Secretory Otitis Media and Children without Middle Ear Effusion.Microorganisms · 2024Article
- Quality of life in children undergoing tonsillectomy: a cross-sectional survey.Italian journal of pediatrics · 2023Article
- 150th Anniversary of global adenoid investigations: unanswered questions and unsolved problems.Frontiers in pediatrics · 2023Review
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Authors and funding
8 authors at 1 institution in 1 country.
Funding
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Abstract
backgroundBacterial infection of adenoid is currently considered to be an important cause of adenoid hypertrophy (AH) in children. Although several bacteriology studies on adenoid diseases have been reported, the aerobic bacterial study regarding risk factors and antibiotic sensitivity of AH in Chinese children is lacking. This study aims to investigate the risk factors for aerobic bacterial colonization of AH in Chinese children and to elucidate aerobic bacterial profiles and antibiotic sensitivity.
methodsSamples were collected from the adenoid core and surface tissue of 466 children undergoing adenoidectomy. Aerobic cultures and antibiotic sensitivity were observed. The risk factors for bacterial colonization of adenoid were analyzed statistically.
resultsA total of 143 children could be detected opportunistic pathogens in adenoid surface and/or core tissue, with a carriage rate of 30.7%. The presence of chronic rhinosinusitis, tonsillar hypertrophy and adenoidal size were the risk factors for aerobic bacterial colonization of adenoid in univariate analysis. Multivariate analysis showed that chronic rhinosinusitis and tonsil hypertrophy were significant variables associated with the aerobic bacterial colonization. The most frequently isolated aerobic bacteria were Haemophilus influenzae, followed by Staphylococcus aureus and Streptococcus pneumoniae. There was no statistically significant difference in bacterial species between the adenoid surface and core. The above common bacteria were more sensitive to cephalosporins and quinolones antibiotics, and significantly resistant to penicillin antibiotics and non-β-lactamase inhibitors.
conclusionOur results provide recent aerobic bacterial profiles for AH among Chinese children and confirm the risk factors and antibiotic sensitivity. This study contributes to understanding the role of different risk factors in the development of AH and will be helpful to the treatment of AH among Chinese children.
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