Evidence map›Paper›PMID 36123653›Full record

ArticleBMC public health2022

Importance of ventilation and occupancy to Mycobacterium tuberculosis transmission rates in congregate settings.

A K Deol, N Shaikh, K Middelkoop, M Mohlamonyane, R G White, N McCreesh

Abstract read
In one paragraph

Article in BMC public health, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Delayed-Type Hypersensitivity toInternational journal of molecular sciences · 2026
    Pooled it
  2. Review
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  10. The repertoire of mutational signatures in tobacco- and non-tobacco-induced oral cancer.Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico · 2023
    Review
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

A K DeolDepartment of Infectious Disease Epidemiology, London School of Hygiene and Tropical Medicine, London, UK. arminder.deol@cepi.net.
N ShaikhDepartment of Infectious Disease Epidemiology, London School of Hygiene and Tropical Medicine, London, UK.
K MiddelkoopThe Desmond Tutu HIV Centre, Institute of Infectious Disease and Molecular Medicine and Department of Medicine, University of Cape Town, Cape Town, South Africa.
M MohlamonyaneThe Desmond Tutu HIV Centre, Institute of Infectious Disease and Molecular Medicine and Department of Medicine, University of Cape Town, Cape Town, South Africa.
R G WhiteDepartment of Infectious Disease Epidemiology, London School of Hygiene and Tropical Medicine, London, UK.
N McCreeshDepartment of Infectious Disease Epidemiology, London School of Hygiene and Tropical Medicine, London, UK.

Funding

Medical Research Council MR/P002404/1Wellcome Trust
6 · The paper itself

Abstract

backgroundVentilation rates are a key determinant of the transmission rate of Mycobacterium tuberculosis and other airborne infections. Targeting infection prevention and control (IPC) interventions at locations where ventilation rates are low and occupancy high could be a highly effective intervention strategy. Despite this, few data are available on ventilation rates and occupancy in congregate locations in high tuberculosis burden settings.

methodsWe collected carbon dioxide concentration and occupancy data in congregate locations and public transport on 88 occasions, in Cape Town, South Africa. For each location, we estimated ventilation rates and the relative rate of infection, accounting for ventilation rates and occupancy.

resultsWe show that the estimated potential transmission rate in congregate settings and public transport varies greatly between different settings. Overall, in the community we studied, estimated infection risk was higher in minibus taxis and trains than in salons, bars, and shops. Despite good levels of ventilation, infection risk could be high in the clinic due to high occupancy levels.

conclusionPublic transport in particular may be promising targets for infection prevention and control interventions in this setting, both to reduce Mtb transmission, but also to reduce the transmission of other airborne pathogens such as measles and SARS-CoV-2.

Indexed as

COVID-19Mycobacterium tuberculosisTuberculosis, Lymph NodeCarbon DioxideHumansSARS-CoV-2South AfricaCarbon DioxideAirborne transmissionInfection controlSouth AfricaTuberculosisVentilation

Identifiers

PMID36123653
PMCPMC9483862

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.