Observational studyBMC psychiatry2022
Prevalence and associated risk factors for anxiety and depression in infertile couples of ART treatment: a cross-sectional study.
Observational study in BMC psychiatry, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06996340 (Effects of White Noise on Pain, Anxiety and Comfort During in Invitro Fertilization), which is not on this map. Cited by 29 papers, 4 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Effects of White Noise on Pain, Anxiety and Comfort During in Invitro Fertilization: a Randomized Controlled Trial
Who cites it
29 citing papers in PubMed, 4 syntheses or guidelines pooled it, 45 citations in OpenAlex.
- Prevalence of psychological problems among individuals and couples during assisted reproductive technology(ART) treatment: a systematic review and meta-analysis.Journal of assisted reproduction and genetics · 2025Pooled it
- Prevalence and risk factors of negative emotions in infertile women: a systematic review and meta-analysis.Frontiers in public health · 2025Pooled it
- Prevalence and contributing factors of depression among women with infertility in low-resource settings: a systematic review and meta-analysis.Frontiers in medicine · 2025Pooled it
- Prevalence of anxiety symptoms in infertile men: a systematic review and meta-analysis.BMC public health · 2024Pooled it
- Stress management through cognitive reconstruction and positive thinking in women with recurrent failed In Vitro Fertilization: a randomized controlled trial.BMC psychiatry · 2025Trial
- [Correlational research on body fat rate and skeletal muscle rate with depression in the population of assisted reproduction].Beijing da xue xue bao. Yi xue ban = Journal of Peking University. Health sciences · 2026Article
- Self-esteem in crisis: Psychosocial adaptation and masculine identity among Chinese men with azoospermia.PloS one · 2026Article
- Psychological depression and its association with oocyte yield and embryo outcomes in infertile women undergoingFrontiers in psychiatry · 2026Article
- Maternal psychiatric disorders before, during, and after pregnancy: a national cohort study in Sweden.Molecular psychiatry · 2026Article
- The prevalence of anxiety, depression and the mediating role in leprosy patients: a nationally representative cross-sectional study.Scientific reports · 2025Article
- A mixed-methods study on negative psychological states of infertile women undergoing assisted reproductive treatment.Scientific reports · 2025Article
- Mental health screening and psychological support should be the standard of care in fertility clinics.Journal of assisted reproduction and genetics · 2025Article
- Factors influencing the anxiety and depression status in patients undergoing in vitro fertilization-embryo transfer assisted pregnancy.Scientific reports · 2025Article
- Psychopharmacological interventions among people who use Assisted Reproductive Technology (ART) - a scoping review.Reproductive biology and endocrinology : RB&E · 2025Article
- Silent battles, global insights: anxiety and depression in the world of assisted reproduction.Journal of assisted reproduction and genetics · 2025Review
- Using network analysis to identify central symptoms of depression and anxiety in different profiles of infertility patients.BMC psychiatry · 2025Article
- Fluvoxamine Inhibited NLRP3 and NF-κB Inflammatory Pathways and Maintained Genital Functions by Ameliorating CD-MPR, KISS-1, AQP4 and Claudin-1 Expressions.Basic & clinical pharmacology & toxicology · 2025Article
- Correlations among hope, fertility quality of life and negative emotions for couples undergoing their first in vitro fertilization-embryo transfer: a cross-sectional analysis.Reproductive health · 2025Article
- Pathway analysis of the impact of family function and self-efficacy on depression and anxiety in patients undergoing in vitro fertilization-embryo transfer.BMC psychology · 2024Article
- Assessing psychological health and reproductive function: Depression, anxiety, and stress in infertile men compared to controls: A case-control study.International journal of reproductive biomedicine · 2024Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundInfertility now is a public health concern and is associated with increased psychological distress.
methodsWe enrolled 1247 infertile couples and assessed their anxiety and depression status before and during assisted reproductive technology (ART) treatment using the Self-Rating Anxiety Scale (SAS) and Self-Rating Depression Scale (SDS). The Chi-square or fisher's exact test was used to analyze the prevalence of anxiety and depression in infertile couples. Multivariate logistical regression was performed to analyze the risk factors for anxiety and depression.
resultsThe prevalence of anxiety was 13.5% and 8.7% (p < 0.05), and that of depression was 9.4% and 7.9% (p = 0.2) in female and male partners, respectively. Female SAS and SDS scores were positively associated with male SAS and SDS scores, respectively (r = 0.52 and r = 0.50, respectively, both p < 0.0001), and were positively associated with their own SDS and SAS scores, respectively (r = 0.63 and r = 0.62, respectively, both p < 0.0001). Their own depression or partners' anxiety was associated with the anxiety, and their own anxiety or partners' depression was associated with the depression in infertile couples. No children, unemployment, and low education level were also associated with female anxiety. SAS and SDS scores were significantly decreased during ART treatment.
conclusionsFemales were more vulnerable to having anxiety than males in infertile couples. Anxiety and depression in infertile couples could interact, therefore, anxiety and depression would be simultaneously counseled, and their partners also should be given supportive psychotherapy.
trial registrationIt was an observational study and had no health care interventions on participants. So it was not registrated.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.