ArticleBMC cardiovascular disorders2022
Drug-related problems and its predictors among hospitalized heart failure patients at Jimma Medical Center, South West Ethiopia: prospective interventional study.
Article in BMC cardiovascular disorders, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 2 of them syntheses that pooled it.
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9 citing papers in PubMed, 2 syntheses or guidelines pooled it, 13 citations in OpenAlex.
- Medication-related problems and contributing factors in patients with cardiovascular disorders in Ethiopia: a systematic review and meta-analysis.Systematic reviews · 2025Pooled it
- Prevalence and predictors of poor heart failure treatment outcomes in Ethiopia: a systematic review and meta-analysis.Frontiers in cardiovascular medicine · 2024Pooled it
- Development and validation of a machine learning-based clinical decision support tool for stratifying intravenous medication risk in hospitalized patients with heart failure.International journal of clinical pharmacy · 2026Article
- Patients' Needs and Expectations for the Application of Prevention of Drug-related Problems Prevention Programs.Journal of research in pharmacy practice · 2026Article
- Drug-related problems in elderly patients with AECOPD and pharmaceutical intervention practice: a prospective study.Frontiers in pharmacology · 2025Article
- Drug Related Problems among Older Inpatients at a Tertiary Care Setting.Journal of clinical medicine · 2024Article
- Drug therapy problems among hospitalized patients with cardiovascular disease.BMC cardiovascular disorders · 2024Observational
- Prevalence and risk factors of mortality among heart failure patients in low resource setting hospitals: a multicenter prospective observational study.Frontiers in cardiovascular medicine · 2024Article
- Drug-related problems identified by clinical pharmacists in an academic medical centre in Thailand.Journal of pharmaceutical policy and practice · 2024Article
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5 authors at 2 institutions in 1 country.
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Abstract
backgroundDrug-related problems are associated with high mortality, complications, prolonged hospital stay, compromised quality of life, and increased healthcare costs. This problem is high in patients hospitalized with chronic conditions such as heart failure. However, there are limited studies conducted on this area, particularly in Ethiopia.
objectiveTo evaluate drug-related problems, their predictors, and clinical pharmacist intervention among hospitalized heart failure patients at Jimma Medical Center, Ethiopia. METHODS AND
participantsA prospective interventional study was conducted among hospitalized heart failure patients from September 30, 2020, to May 28, 2021, at Jimma Medical Center. Drug-related problems were sorted based on the Pharmaceutical Care Network Europe drug classification tool version 9.0. Patient's specific data were collected using a structured questionnaire. Data was analyzed using statistical software package version 23.0. Multivariate logistic regression analysis was used to identify independent predictors of drug-related problems occurrence and statistical significance was considered at a p value < 0.05.
resultsA total of 237 heart failure patients were included in this study. The mean (SD) age was 49.06 + 17.79. About two-thirds (66.2%) of study patients had at least one drug-related problem during their hospital stay. A total of 283 drug-related problems were identified among 157 patients. Treatment effectiveness-related problem (55.48%) was the most common observed drug-related problem. The independent predictors of drug-related problems were khat chewing [AOR = 3.25, 95% CI = (1.46-7.23)], hospital stay > 18 days [AOR = 3.77, 95% CI = (1.93-7.37)]; presence of comorbid condition [AOR = 2.59, 95% CI = (1.35-4.96)] and polypharmacy [AOR = 2.94, 95% CI = (1.54-5.61)].
conclusionThe prevalence of drug-related problems was high among hospitalized heart failure patients in the study area. Chewing khat, prolonged hospital stay, comorbidity, and polypharmacy were the predictors of drug-related problems. Hence, to overcome these problems, clinical pharmacists, physicians, and other health professionals have to work in collaboration.
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