ArticleBMC geriatrics2022
Risk factors of frailty and functional disability in community-dwelling older adults: a cross-sectional analysis of the FREEDOM-LNA cohort study.
Article in BMC geriatrics, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
17 citing papers in PubMed, 2 syntheses or guidelines pooled it, 29 citations in OpenAlex.
- Functional disability in basic and instrumental activities of daily living among older adults globally: a systematic review and meta-analysis.BMC geriatrics · 2025Pooled it
- Association between Drug Therapy and Risk of Incident Frailty: A Systematic Review.Annals of geriatric medicine and research · 2024Pooled it
- Oral functional limitation and risk of frailty onset in older adults: a sex-stratified 4-Year cohort study with competing risk analysis.GeroScience · 2026Article
- Examining HbA1c in Frail Older Adults: A Linked Data Cohort Study.Australasian journal on ageing · 2026Article
- Pain and depression mediate the relationship between multimorbidity and frailty in older adults with diabetes.Scientific reports · 2026Article
- Sarcopenia, Obesity, and Sarcopenic Obesity in Relation to Functional Limitations in Older Adults.Journal of clinical medicine · 2026Article
- Medication Use by Older Adults with Frailty: A Scoping Review.Pharmacy (Basel, Switzerland) · 2025Review
- Development of a physical performance summary score in middle age: Findings from the CARDIA Function study.American journal of epidemiology · 2025Article
- Observational
- Building Research Infrastructure to Address Psychosocial Frailty and Reach Underserved Aging Populations.Journal of psychosocial nursing and mental health services · 2025Article
- The Impact of Aerobic Exercise on Health Management in Older Patients with Hypertension: A Systematic Review of Randomized Controlled Trials from the Past Decade.International journal of general medicine · 2025Review
- Risk factors of frailty/sarcopenia in community older adults: Meta-analysis.Open medicine (Warsaw, Poland) · 2025Review
- A Method for Assessing the Prevalence of Food Insecurity in Older Adults Based on Resource Constraints and Food-Related Physical Functioning Limitations.Current developments in nutrition · 2024Article
- Osteosarcopenia predicts greater risk of functional disability than sarcopenia: a longitudinal analysis of FraDySMex cohort study.The journal of nutrition, health & aging · 2024Article
- Functional fitness and physical independence in later years: cut-off values and validation.BMC geriatrics · 2024Article
- Relationship between intrinsic capacity and health-related quality of life among community-dwelling older adults: the moderating role of social support.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2024Article
- Liver transplantation in the patient with physical frailty.Journal of hepatology · 2023Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
10 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundFrailty is a geriatric syndrome associated with disability and negative health outcome. To determine the factors associated with frailty and functional disability in older participants living in community in France. We included 753 community-dwelling old participants with available frailty data at baseline.
resultsOverall, 31.9% were frail, 58.3% were prefrail, and 9.8% were robust. The SMAF (French acronym for Functional Autonomy Measurement System) score was significantly lower (mean ± standard deviation: -25.8 ± 11.2) in frail participants compared to prefrail (-14.3 ± 9.7) or robust participants (-8.1 ± 7.0); 82% of frail older participants had limitation in at least one ADL and 97.5% in at least one IADL compared to 54.2 and 76.8%, respectively of pre-frail and 29.7 and 47.3% of robust participants. Age, depression, impaired cognition and diabetes were significantly associated with higher odds of frailty. These variables were also strongly associated with functional disability. Female gender, polypharmacy, and smoking were additional variables significantly associated with degraded SMAF and/or ADL/IADL.
conclusionsThis study showed that functional disability increased proportionally to frailty, and depression, cognitive decline and diabetes are modifiable risk factors significantly associated with frailty and functional disability.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.