Evidence map›Paper›PMID 36123360›Full record

ArticleScientific reports2022

Utility of fatty acid profile and in vitro immune cell activation for chemical and biological standardization of Arthrospira/Limnospira.

Jungmoo Huh, Jin Zhang, Radka Hauerová, Joseph Lee, Saqlain Haider, Mei Wang, Tomáš Hauer, Ikhlas A Khan, Amar G Chittiboyina, Nirmal D Pugh

Abstract read
In one paragraph

Article in Scientific reports, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Jungmoo HuhNational Center for Natural Products Research, Research Institute of Pharmaceutical Sciences, School of Pharmacy, The University of Mississippi, University, MS, 38677, USA.
Jin ZhangNational Center for Natural Products Research, Research Institute of Pharmaceutical Sciences, School of Pharmacy, The University of Mississippi, University, MS, 38677, USA.
Radka HauerováFaculty of Science, University of South Bohemia, Branišovská 1760, 370 05, České Budějovice, Czech Republic.
Joseph LeeNational Center for Natural Products Research, Research Institute of Pharmaceutical Sciences, School of Pharmacy, The University of Mississippi, University, MS, 38677, USA.
Saqlain HaiderNational Center for Natural Products Research, Research Institute of Pharmaceutical Sciences, School of Pharmacy, The University of Mississippi, University, MS, 38677, USA.
Mei WangNatural Products Utilization Research Unit, Agricultural Research Service, United States Department of Agriculture, University, MS, 38677, USA.
Tomáš HauerFaculty of Science, University of South Bohemia, Branišovská 1760, 370 05, České Budějovice, Czech Republic.
Ikhlas A KhanNational Center for Natural Products Research, Research Institute of Pharmaceutical Sciences, School of Pharmacy, The University of Mississippi, University, MS, 38677, USA.
Amar G ChittiboyinaNational Center for Natural Products Research, Research Institute of Pharmaceutical Sciences, School of Pharmacy, The University of Mississippi, University, MS, 38677, USA. amar@olemiss.edu.
Nirmal D PughNational Center for Natural Products Research, Research Institute of Pharmaceutical Sciences, School of Pharmacy, The University of Mississippi, University, MS, 38677, USA. ndpugh@olemiss.edu.

Funding

Unravelling Immune Enhancement by ImmulinaU19AT010838 · NCCIH · UNIVERSITY OF MISSISSIPPI · PI MARSHALL, GAILEN D. · 2020 to 2024
$6.1M
NCCIH NIH HHS U19 AT010838NIH HHS U19AT010838
6 · The paper itself

Abstract

Commercially cultivated Limnospira (species formerly classified to genus Arthrospira) is a popular food/supplement consumed by millions of people worldwide for health benefits. The objective of the current research was to advance the standardization technology for Limnospira. Quantitative methods were established to detect fatty acids as potential chemical markers and immune-enhancing activity. Analysis of 20 different batches of biomass obtained from one commercial grower demonstrated that there was a statistically significant relationship between the sum of two fatty acids (linoleic and γ-linolenic) and Toll-like receptor (TLR)2/TLR1-dependent activation (R

Indexed as

SpirulinaFatty AcidsHumansReference StandardsToll-Like Receptor 1Toll-Like Receptor 2Fatty AcidsToll-Like Receptor 1Toll-Like Receptor 2

Identifiers

PMID36123360
PMCPMC9485217

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.