Evidence map›Paper›PMID 36123280›Full record

ReviewEuropean urology focus2022

Liquid Biopsy for Prostate and Bladder Cancer: Progress and Pitfalls.

Levi Groen, Jack Schalken

Open access · hybridAbstract readReview
PubMed Publisher
In one paragraph

Review in European urology focus, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
3.3field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 17 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
  4. Article
  5. A scoping review of factors influencing the implementation of liquid biopsy for cancer care.Journal of experimental & clinical cancer research : CR · 2025
    Article
  6. Article
  7. Review
  8. Review
  9. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Levi GroenRadboud Institute for Life Sciences, Radboudumc, Nijmegen, The Netherlands. Electronic address: levi.groen@radboudumc.nl.
Jack SchalkenRadboud Institute for Life Sciences, Radboudumc, Nijmegen, The Netherlands. Electronic address: jack.schalken@radboudumc.nl.
Radboud Institute for Molecular Life Sciences · NL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Urinary liquid biopsy (LB) tests have contributed to reducing overtreatment and improving the detection of bladder and prostate cancer. Circulating tumor cells, DNA, and RNA are the focus of next-generation blood-based LB tests. These tests aim to stratify risk according to the detection of resistance and recurrence markers in patients with metastatic disease. The costs, lack of standardization, reimbursement challenges, and specialized workflows associated with characterization of blood-derived biomarkers are the primary barriers to their clinical implementation. This review provides an overview of the successes and pitfalls of LB-based tests for bladder and prostate cancer. PATIENT SUMMARY: Urinary and blood-based liquid biopsy tests are minimally invasive and highly efficacious in detecting clinically significant cancer.

Indexed as

Prostatic NeoplasmsUrinary Bladder NeoplasmsBiomarkers, TumorDNAHumansLiquid BiopsyMaleProstateRNABiomarkers, TumorDNARNABladder cancerLiquid biopsyPrecision therapyProstate cancer

Identifiers

PMID36123280
OpenAlexW4296195899

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.