Evidence map›Paper›PMID 36123116›Full record

ArticleeNeuro

Endogenous Circadian Clock Machinery in Cortical NG2-Glia Regulates Cellular Proliferation.

Terry Dean, Aissia Victoria Koffi, Evan Goldstein, Javid Ghaemmaghami, Vittorio Gallo

Open access · goldAbstract read
In one paragraph

Article in eNeuro. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.4field-weighted citation impact, top 45% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 2 countries.

Terry DeanCenter for Neuroscience Research, Children's National Hospital, Washington, DC 20010 tdean@childrensnational.org vgallo@childrensnational.org.ORCID https://orcid.org/0000-0002-8869-2464
Aissia Victoria KoffiCenter for Neuroscience Research, Children's National Hospital, Washington, DC 20010.
Evan GoldsteinCenter for Neuroscience Research, Children's National Hospital, Washington, DC 20010.ORCID https://orcid.org/0000-0002-8052-7405
Javid GhaemmaghamiCenter for Neuroscience Research, Children's National Hospital, Washington, DC 20010.
Vittorio GalloCenter for Neuroscience Research, Children's National Hospital, Washington, DC 20010.
National Hospital · INChildren's National · USHoward University · US

Funding

Neurobehavioral Evaluation CoreP50HD105328 · NICHD · CHILDREN'S RESEARCH INSTITUTE · PI LAUREN KENWORTHY · 2021 to 2026
$9.3M
Child Health Research Career Development Award (CHRCDA) Program at Children's NationalK12HD001399 · NICHD · CHILDREN'S RESEARCH INSTITUTE · PI NATHAN KUPPERMANN · 2001 to 2026
$9.1M
Research_ProjectU54HD090257 · NICHD · CHILDREN'S RESEARCH INSTITUTE · PI VITTORIO GALLO, VITTORIO GALLO VITTORIO GALLO · 2016 to 2020
$5.9M
Mechanisms of Oligodendrocyte and Axonal Abnormalities After Perinatal Brain InjuryR37NS109478 · NINDS · SEATTLE CHILDREN'S HOSPITAL · PI GALLO, VITTORIO · 2018 to 2025
$3.1M
NICHD NIH HHS K12 HD001399NICHD NIH HHS P50 HD105328NICHD NIH HHS U54 HD090257NINDS NIH HHS R37 NS109478
6 · The paper itself

Abstract

The molecular circadian clock can be found throughout the body and is essential for the synchronizing cellular physiology with the 24 h day. However, the role of the clock in regulating the regenerative potential of the brain has not been explored. We report here that murine NG2-glia, the largest population of proliferative cells in the mature central nervous system, rhythmically express circadian clock genes in a 24 h period, including the critical clock component

Indexed as

ARNTL Transcription FactorsCircadian ClocksAnimalsCell ProliferationCircadian RhythmMiceNeurogliaRNAARNTL Transcription FactorsRNABmal1circadianNG2-gliaOPC

Identifiers

PMID36123116
PMCPMC9536852
OpenAlexW4296344177

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.