ArticleBMJ open2022
Epidemiology, diagnostics and factors associated with mortality during a cholera epidemic in Nigeria, October 2020-October 2021: a retrospective analysis of national surveillance data.
Article in BMJ open, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 1 of them a synthesis that pooled it.
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Who cites it
20 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Cholera in Lagos State, Nigeria: a One Health perspective on outbreaks and public health interventions.Frontiers in public health · 2026Pooled it
- Predictors of mortality from diarrhea during a cholera outbreak in Haiti's Artibonite and Centre regions, 2022-2024.PLoS neglected tropical diseases · 2026Article
- Determinants of recovery time from cholera in a conflict-affected agro-pastoral region of ethiopia: evidence from survival models.Conflict and health · 2026Article
- Factors associated with in-hospital mortality during the 2023 cholera outbreak in Hammanskraal, South Africa: a cross-sectional study.BMC infectious diseases · 2026Article
- Recurrent outbreaks of cholera in Nigeria: a narrative review on the role of conflict and climate change.Journal of water and health · 2026Review
- Strengthening disaster preparedness and health security in Niger state, Nigeria through a WHO STAR-based multi-hazard risk assessment.Scientific reports · 2026Article
- Cholera in Nigeria: a five-decade review of outbreak dynamics and health system responses.Journal of health, population, and nutrition · 2025Review
- Exploring the Impact of Traditional Practices onInternational journal of environmental research and public health · 2025Article
- Cholera Outbreak in Nigeria: History, Review of Socioeconomic and Meteorological Drivers, Diagnostic Challenges, and Artificial Intelligence Integration.Global health, epidemiology and genomics · 2025Review
- Determinants of cholera fatalities in Malawi: A case-control study of patient-level and clinical management factors in the 2022-23 outbreak.PLOS global public health · 2025Article
- Enablers and barriers to implementing cholera interventions in Nigeria: a community-based system dynamics approach.Health policy and planning · 2024Article
- Unmasking the Neglected Cholera Outbreaks in Sub-Saharan Africa.International journal of public health · 2024Article
- Influences of community engagement and health system strengthening for cholera control in cholera reporting countries.BMJ global health · 2023Article
- Unlocking the power of molecular and genomics tools to enhance cholera surveillance in Africa.Nature medicine · 2023Article
- The interplay among conflict, water scarcity, and cholera in Northern Nigeria.Public health challenges · 2023Article
- Resource availability and capacity to implement multi-stranded cholera interventions in the north-east region of Nigeria.BMC global and public health · 2023Article
- Development of a Scorecard to Monitor Progress toward National Cholera Elimination: Its Application in Uganda.The American journal of tropical medicine and hygiene · 2023Review
- Healthcare workers knowledge of cholera multi-stranded interventions and its determining factors in North-East Nigeria: planning and policy implications.Human resources for health · 2023Article
- Cholera's global resurgence: urgent appeal for enhanced vaccine availability in Nigeria, and beyond.Therapeutic advances in infectious diseaseArticle
- Cholera in Nigeria: A review of outbreaks, trends, contributing factors, and public health responses.Nigerian medical journal : journal of the Nigeria Medical AssociationReview
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Abstract
objectivesNigeria reported an upsurge in cholera cases in October 2020, which then transitioned into a large, disseminated epidemic for most of 2021. This study aimed to describe the epidemiology, diagnostic performance of rapid diagnostic test (RDT) kits and the factors associated with mortality during the epidemic.
designA retrospective analysis of national surveillance data.
setting33 of 37 states (including the Federal Capital Territory) in Nigeria.
participantsPersons who met cholera case definition (a person of any age with acute watery diarrhoea, with or without vomiting) between October 2020 and October 2021 within the Nigeria Centre for Disease Control surveillance data. OUTCOME MEASURES: Attack rate (AR; per 100 000 persons), case fatality rate (CFR; %) and accuracy of RDT performance compared with culture using area under the receiver operating characteristic curve (AUROC). Additionally, individual factors associated with cholera deaths and hospitalisation were presented as adjusted OR with 95% CIs.
resultsOverall, 93 598 cholera cases and 3298 deaths (CFR: 3.5%) were reported across 33 of 37 states in Nigeria within the study period. The proportions of cholera cases were higher in men aged 5-14 years and women aged 25-44 years. The overall AR was 46.5 per 100 000 persons. The North-West region recorded the highest AR with 102 per 100 000. Older age, male gender, residency in the North-Central region and severe dehydration significantly increased the odds of cholera deaths. The cholera RDT had excellent diagnostic accuracy (AUROC=0.91; 95% CI 0.87 to 0.96).
conclusionsCholera remains a serious public health threat in Nigeria with a high mortality rate. Thus, we recommend making RDT kits more widely accessible for improved surveillance and prompt case management across the country.
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