ReviewArchives of biochemistry and biophysics2022
Selenium status and type 2 diabetes risk.
Review in Archives of biochemistry and biophysics, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
16 citing papers in PubMed, 18 citations in OpenAlex.
- Current Advances in the Physiological Roles of the Thioredoxin-Like Family of Selenoproteins.Biological trace element research · 2026Review
- Targeted Supplementation and Nutritional Strategies for Healthy Aging: A Review of Physiological and Molecular Benefits.Current nutrition reports · 2026Review
- Selenium and selenoproteins in age-related metabolic diseases: mechanistic insights and translational perspectives.Frontiers in nutrition · 2026Review
- Biosafety and pharmacokinetic characteristics of polyethylene pyrrolidone modified nano selenium in rats.BMC biotechnology · 2024Article
- Mobile Application and Machine Learning-Driven Scheme for Intelligent Diabetes Progression Analysis and Management Using Multiple Risk Factors.Bioengineering (Basel, Switzerland) · 2024Article
- An epigenome-wide study of selenium status and DNA methylation in the Strong Heart Study.Environment international · 2024Article
- Comprehensive Insights into the Health Effects of Selenium Exposure and Supplementation Among the Chinese Community Middle-Aged and Elderly: a Combined Retrospective Cohort Study and Intervention Study.Biological trace element research · 2024Article
- Serum selenium and fasting blood glucose: a cross-sectional study in women of different menopause status.BMC women's health · 2024Article
- Effect of trace elements and nutrients on diabetes and its complications: a Mendelian randomization study.Frontiers in nutrition · 2024Article
- The Regulation of Selenoproteins in Diabetes: A New Way to Treat Diabetes.Current pharmaceutical design · 2024Review
- Protective Effects of Different Selenium Green Tea Polysaccharides on the Development of Type 2 Diabetes in Mice.Foods (Basel, Switzerland) · 2023Article
- Deciphering the Role of Selenoprotein M.Antioxidants (Basel, Switzerland) · 2023Review
- Dose-response relationship between dietary antioxidant intake and diabetic kidney disease in the US adults with diabetes.Acta diabetologica · 2023Article
- Composite dietary antioxidant index was negatively associated with the prevalence of diabetes independent of cardiovascular diseases.Diabetology & metabolic syndrome · 2023Article
- Selenium Protects Mouse Hypothalamic Cells from Glucocorticoid-Induced Endoplasmic Reticulum Stress Vulnerability and Insulin Signaling Impairment.Antioxidants (Basel, Switzerland) · 2023Article
- Selenium in Bodily Homeostasis: Hypothalamus, Hormones, and Highways of Communication.International journal of molecular sciences · 2022Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 3 institutions in 1 country.
Funding
Abstract
Optimal selenium (Se) status is necessary for overall health. That status can be affected by food intake pattern, age, sex, and health status. At nutritional levels of intake, Se functions metabolically as an essential constituent of some two dozen selenoproteins, most, if not all, of which have redox functions. Insufficient dietary intake of Se reduces, to varying degrees, the expression of these selenoproteins. Recent clinical and animal studies have indicated that both insufficient and excessive Se intakes may increase risk of type 2 diabetes mellitus (T2D), perhaps by way of selenoprotein actions. In this review, we discuss the current evidence linking Se status and T2D risk, and the roles of 14 selenoproteins and other proteins involved in selenoprotein biosynthesis. Understanding such results can inform the setting of safe and adequate Se intakes.
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Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.