Evidence map›Paper›PMID 36122593›Full record

ArticleApplied clinical informatics2022

Leveraging and Improving Refill Protocols at Your Health System.

Jeffrey T Tokazewski, Maryanne Peifer, John T Howell

Abstract read
In one paragraph

Article in Applied clinical informatics, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Empowering Medication Refills Through Digital Patient Portals.Global journal on quality and safety in healthcare · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Jeffrey T TokazewskiOffice of the Chief Medical Information Officer, Penn Medicine, Philadelphia, Pennsylvania, United States.
Maryanne PeiferOffice of the Chief Medical Information Officer, Penn Medicine, Philadelphia, Pennsylvania, United States.
John T HowellOffice of the Chief Medical Information Officer, Penn Medicine, Philadelphia, Pennsylvania, United States.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesMedication refill processing is a repetitive and predictable time-intensive task for ambulatory primary and specialty care. Refill protocols are a clinical decision support (CDS) tool that allows clinicians to quickly and safely determine appropriateness of a refill request. Our health system opted to improve the quality and breadth of electronic health record vendor-supplied protocols to consistently leverage best practices and emerging evidence and to create novel protocols that further support clinicians.

methodsWe established a refill protocol governance group to guide new protocol build and to review existing protocols regularly to keep current with emerging guidelines. Data-driven prioritization was used to create new protocols for the most frequently refilled medications, as well as for less-prescribed but higher risk medications. Ad-hoc specialist inclusion as subject-matter experts provided greater detail, accuracy, and broader consensus in protocol criteria.

resultsApproximately 11 million refills are processed each year by our health system's providers. The proportion of refill requests supported by a protocol increased over a 2-year period from 49 to 82%, representing a net increase of 3.63 million refills in the second measurement year as compared to the start of the first measurement year. All published refill protocols were reviewed by the governance group over the measurement years for compliance with clinical guidelines. In addition to the structure of the refill protocols' CDS, the process was supported by filters that enable practices to quickly approve refills that pass protocol, providing more time for clinicians to review refills that fail a protocol or for which no protocol exists.

conclusionA refill protocol is a valuable CDS tool that can improve efficiency, effectiveness, and user satisfaction when processing refill requests. A refill protocol governance structure is an effective way to review, edit, and build refill protocols within a health system.

Indexed as

Ambulatory Care FacilitiesElectronic Health RecordsSpecialization

Identifiers

PMID36122593
PMCPMC9646402

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.