Evidence map›Paper›PMID 36121830›Full record

Trial reportPloS one2022

Impact of systematic medication review in emergency department on patients' post-discharge outcomes-A randomized controlled clinical trial.

Lisbeth Damlien Nymoen, Trude Eline Flatebø, Tron Anders Moger, Erik Øie, Espen Molden, Kirsten Kilvik Viktil

Registry-linked trialOpen access · goldAbstract readRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in PloS one, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03123640 (Improving Drug Safety in Emergency Patients -a Randomized Controlled Trial), which is not on this map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
2.3field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03123640 nacompletednot on this map

Improving Drug Safety in Emergency Patients -a Randomized Controlled Trial

TypeinterventionalSponsorDiakonhjemmet HospitalRan2017 to 2022Enrolled806ConditionsMedication Compliance, Drug-Related Side Effects and Adverse Reactions, Remission, Medicinal SubstanceArmsMedication reconciliation and medication review
3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 9 citations in OpenAlex.

  1. Trial
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Review
  8. Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Lisbeth Damlien NymoenDiakonhjemmet Hospital Pharmacy AS, Oslo, Norway.ORCID 0000-0001-9330-3374
Trude Eline FlatebøDiakonhjemmet Hospital Pharmacy AS, Oslo, Norway.
Tron Anders MogerDepartment of Health Management and Health Economics, University of Oslo, Oslo, Norway.
Erik ØieDepartment of Internal Medicine, Diakonhjemmet Hospital, Oslo, Norway.
Espen MoldenDepartment of Pharmacy, University of Oslo, Oslo, Norway.
Kirsten Kilvik ViktilDiakonhjemmet Hospital Pharmacy AS, Oslo, Norway.
University of Oslo · NODiakonhjemmet Hospital · NO

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionThe main objective of this study was to investigate whether systematic medication review conducted by clinical pharmacists can impact clinical outcomes and post-discharge outcomes for patients admitted to the emergency department.

methodThis parallel group, non-blinded, randomized controlled trial was conducted in the emergency department, Diakonhjemmet Hospital, Oslo, Norway. The study was registered in ClinicalTrials.gov, Identifier: NCT03123640 in April 2017. From April 2017 to May 2018, patients ≥18 years were included and randomized (1:1) to intervention- or control group. The control group received standard care from emergency department physicians and nurses. In addition to standard care, the intervention group received systematic medication review including medication reconciliation conducted by pharmacists, during the emergency department stay. The primary outcome was proportion of patients with an unplanned contact with hospital within 12 months from inclusion stay discharge.

resultsIn total, 807 patients were included and randomized, 1:1, to intervention or control group. After excluding 8 patients dying during hospital stay and 10 patients lacking Norwegian personal identification number, the primary analysis comprised 789 patients: 394 intervention group patients and 395 control group patients. Regarding the primary outcome, there was no significant difference in proportion of patients with an unplanned contact with hospital within 12 months after inclusion stay discharge between groups (51.0% of intervention group patients vs. 53.2% of control group patients, p = 0.546).

conclusionAs currently designed, emergency department pharmacist-led medication review did not significantly influence clinical- or post-discharge outcomes. This study did, however pinpoint important practical implementations, which can be used to design tailored pharmacist-led interventions and workflow regarding drug-related issues in the emergency department setting.

Indexed as

AftercarePatient DischargeEmergency Service, HospitalHumansMedication ReconciliationMedication Review

Identifiers

PMID36121830
PMCPMC9484649
OpenAlexW4296324834

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.