Evidence map›Paper›PMID 36121804›Full record

ArticlePloS one2022

Neurotrauma clinicians' perspectives on the contextual challenges associated with traumatic brain injury follow up in low-income and middle-income countries: A reflexive thematic analysis.

Brandon G Smith, Charlotte J Whiffin, Ignatius N Esene, Claire Karekezi, Tom Bashford, Muhammad Mukhtar Khan, Davi J Fontoura Solla, Bhagavatula Indira Devi, Wellingson S Paiva, Franco Servadei and 4 more

Abstract read
In one paragraph

Article in PloS one, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Pediatric Traumatic Brain Injury and Healthcare-associated Infections: A Prospective Study on Determinants of Mortality Using Least Absolute Shrinkage and Selection Operator Regression.Indian journal of critical care medicine : peer-reviewed, official publication of Indian Society of Critical Care Medicine · 2026
    Article
  3. Article
  4. Article
  5. The role of advocacy and policy in advancing global neurosurgery.Annals of medicine and surgery (2012) · 2025
    Review
  6. Review
  7. Article
  8. Article
  9. Article
  10. Article
  11. Cerebral Net Water Uptake in Posttraumatic Cerebral Ischemia.Advances in experimental medicine and biology · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Brandon G SmithDivision of Neurosurgery, Department of Clinical Neurosciences, Addenbrooke's Hospital and University of Cambridge, Cambridge, United Kingdom.ORCID 0000-0001-8471-1368
Charlotte J WhiffinNIHR Global Health Research Group on Neurotrauma, University of Cambridge, Cambridge, United Kingdom.
Ignatius N EseneNeurosurgery Division, Faculty of Health Sciences, University of Bamenda, Bambili, Cameroon.
Claire KarekeziNeurosurgery Unit, Department of Surgery, Rwanda Military Hospital, Kigali, Rwanda.ORCID 0000-0002-7183-899X
Tom BashfordNIHR Global Health Research Group on Neurotrauma, University of Cambridge, Cambridge, United Kingdom.ORCID 0000-0003-0228-9779
Muhammad Mukhtar KhanNIHR Global Health Research Group on Neurotrauma, University of Cambridge, Cambridge, United Kingdom.
Davi J Fontoura SollaNIHR Global Health Research Group on Neurotrauma, University of Cambridge, Cambridge, United Kingdom.ORCID 0000-0002-5092-6595
Bhagavatula Indira DeviNIHR Global Health Research Group on Neurotrauma, University of Cambridge, Cambridge, United Kingdom.
Wellingson S PaivaNIHR Global Health Research Group on Neurotrauma, University of Cambridge, Cambridge, United Kingdom.
Franco ServadeiHumanitas Research Hospital-IRCCS and Humanitas University, Rozzano, Milan, Italy.
Peter J HutchinsonDivision of Neurosurgery, Department of Clinical Neurosciences, Addenbrooke's Hospital and University of Cambridge, Cambridge, United Kingdom.
Angelos G KoliasDivision of Neurosurgery, Department of Clinical Neurosciences, Addenbrooke's Hospital and University of Cambridge, Cambridge, United Kingdom.
Anthony FigajiNIHR Global Health Research Group on Neurotrauma, University of Cambridge, Cambridge, United Kingdom.
Andres M RubianoNIHR Global Health Research Group on Neurotrauma, University of Cambridge, Cambridge, United Kingdom.

Funding

Department of Health 16/137/105
6 · The paper itself

Abstract

backgroundTraumatic brain injury (TBI) is a major global health issue, but low- and middle-income countries (LMICs) face the greatest burden. Significant differences in neurotrauma outcomes are recognised between LMICs and high-income countries. However, outcome data is not consistently nor reliably recorded in either setting, thus the true burden of TBI cannot be accurately quantified.

objectiveTo explore the specific contextual challenges of, and possible solutions to improve, long-term follow-up following TBI in low-resource settings.

methodsA cross-sectional, pragmatic qualitative study, that considered knowledge subjective and reality multiple (i.e. situated within the naturalistic paradigm). Data collection utilised semi-structured interviews, by videoconference and asynchronous e-mail. Data were analysed using Braun and Clarke's six-stage Reflexive Thematic Analysis.

results18 neurosurgeons from 13 countries participated in this study, and data analysis gave rise to five themes: Clinical Context: What must we understand?; Perspectives and Definitions: What are we talking about?; Ownership and Beneficiaries: Why do we do it?; Lost to Follow-up: Who misses out and why?; Processes and Procedures: What do we do, or what might we do?

conclusionThe collection of long-term outcome data plays an imperative role in reducing the global burden of neurotrauma. Therefore, this was an exploratory study that examined the contextual challenges associated with long-term follow-up in LMICs. Where technology can contribute to improved neurotrauma surveillance and remote assessment, these must be implemented in a manner that improves patient outcomes, reduces clinical burden on physicians, and does not surpass the comprehension, capabilities, or financial means of the end user. Future research is recommended to investigate patient and family perspectives, the impact on clinical care teams, and the full economic implications of new technologies for follow-up.

Indexed as

Brain Injuries, TraumaticDeveloping CountriesCross-Sectional StudiesFollow-Up StudiesHumansIncome

Identifiers

PMID36121804
PMCPMC9484678

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.