Evidence map›Paper›PMID 36121298›Full record

ArticleJournal of virology2022

Heparin Protects Human Neural Progenitor Cells from Zika Virus-Induced Cell Death While Preserving Their Differentiation into Mature Neuroglial Cells.

Isabel Pagani, Linda Ottoboni, Paola Podini, Silvia Ghezzi, Elena Brambilla, Svetlana Bezukladova, Davide Corti, Marco Emilio Bianchi, Maria Rosaria Capobianchi, Guido Poli and 4 more

Open access · hybridAbstract read
In one paragraph

Article in Journal of virology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.6field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 8 citations in OpenAlex.

  1. Article
  2. Paraptosis-A Distinct Pathway to Cell Death.International journal of molecular sciences · 2024
    Review
  3. Article
  4. Article
  5. Article
  6. Neurogenesis and Viral Infection.Frontiers in immunology · 2022
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 5 institutions in 3 countries.

Isabel PaganiSan Raffaele Scientific Institute, Milan, Italy.ORCID 0000-0001-5396-0740
Linda OttoboniSan Raffaele Scientific Institute, Milan, Italy.
Paola PodiniSan Raffaele Scientific Institute, Milan, Italy.
Silvia GhezziSan Raffaele Scientific Institute, Milan, Italy.
Elena BrambillaSan Raffaele Scientific Institute, Milan, Italy.
Svetlana BezukladovaSan Raffaele Scientific Institute, Milan, Italy.
Davide CortiHumabs Biomed SA, a subsidiary of Vir Biotechnology, Bellinzona, Switzerland.
Marco Emilio BianchiSan Raffaele Scientific Institute, Milan, Italy.
Maria Rosaria CapobianchiNational Institute for Infectious Diseases, "Lazzaro Spallanzani," IRCCS, Rome, Italy.
Guido PoliSan Raffaele Scientific Institute, Milan, Italy.
Paola Panina-BordignonSan Raffaele Scientific Institute, Milan, Italy.
Edwin A YatesDepartment of Biochemistry and Systems Biology, ISMIB, University of Liverpool, Liverpool, United Kingdom.
Gianvito MartinoSan Raffaele Scientific Institute, Milan, Italy.
Elisa VicenziSan Raffaele Scientific Institute, Milan, Italy.ORCID 0000-0003-0051-3968
San Raffaele University of Rome · ITVita-Salute San Raffaele University · ITIstituto Nazionale per le Malattie Infettive Lazzaro Spallanzani · ITUniversity of Liverpool · GBVir Biotechnology (Switzerland) · CH

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Zika virus (ZIKV) is an arbovirus member of the

Indexed as

HeparinNeural Stem CellsNeuroprotective AgentsZika VirusAnticoagulantsAntiviral AgentsCell DeathCell DifferentiationHumansNeurogliaVirus ReplicationZika Virus InfectionAnticoagulantsAntiviral AgentsHeparinNeuroprotective Agentscell deathcell differentiationheparinneural progenitor cellsneuroglial cellsZIKV

Identifiers

PMID36121298
PMCPMC9555206
OpenAlexW4296325220

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.