Evidence map›Paper›PMID 36121238›Full record

ArticleMicrobiology spectrum2022

Clinical Laboratory Utility of a Humanized Antibody in Commercially Available Enzyme Immunoassays for Coccidioidomycosis.

Francisca J Grill, Collin Jugler, Erin Kaleta, Qiang Chen, D Mitchell Magee, Thomas E Grys, Douglas F Lake

Open access · goldAbstract read
In one paragraph

Article in Microbiology spectrum, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.2field-weighted citation impact, top 48% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Francisca J GrillSchool of Life Sciences, Arizona State Universitygrid.215654.1, Tempe, Arizona, USA.
Collin JuglerSchool of Life Sciences, Arizona State Universitygrid.215654.1, Tempe, Arizona, USA.
Erin KaletaDepartment of Laboratory Medicine and Pathology, Mayo Clinicgrid.66875.3a, Phoenix, Arizona, USA.
Qiang ChenSchool of Life Sciences, Arizona State Universitygrid.215654.1, Tempe, Arizona, USA.
D Mitchell MageeCenter for Personalized Diagnostics, Biodesign Institute, Arizona State Universitygrid.215654.1, Tempe, Arizona, USA.
Thomas E GrysDepartment of Laboratory Medicine and Pathology, Mayo Clinicgrid.66875.3a, Phoenix, Arizona, USA.ORCID 0000-0002-0503-124X
Douglas F LakeSchool of Life Sciences, Arizona State Universitygrid.215654.1, Tempe, Arizona, USA.ORCID 0000-0001-8118-9666
Arizona State University · USMayo Clinic Hospital · US

Funding

Serological Biomarkers for CoccidioidomycosisR01AI155954 · NIAID · ARIZONA STATE UNIVERSITY-TEMPE CAMPUS · PI LAKE, DOUGLAS F., MAGEE, D MITCHELL · 2021 to 2024
$1.5M
Optimization of antigen preparations from Coccidioides for diagnostic testingR21AI152042 · NIAID · MAYO CLINIC ARIZONA · PI GRYS, THOMAS E, LAKE, DOUGLAS F. · 2021 to 2022
$415k
NIAID NIH HHS R01 AI155954NIAID NIH HHS R21 AI152042
6 · The paper itself

Abstract

Coccidioidomycosis, also called valley fever (VF), is a fungal infection with endemicity in desert regions of the western United States as well as certain arid regions of Central and South America. Laboratory-based diagnosis of VF often relies on the composite results from three serologic-based diagnostics, complement fixation, immunodiffusion, and enzyme immunoassay (EIA). EIA is commonly performed in clinical laboratories because results can be obtained in a few hours. Two commercially available EIAs, IMMY clarus

Indexed as

CoccidioidomycosisAntibodies, FungalAntibodies, MonoclonalCoccidioidesHumansImmunoenzyme TechniquesImmunoglobulin GImmunoglobulin MLaboratories, ClinicalSensitivity and SpecificityAntibodies, FungalAntibodies, MonoclonalImmunoglobulin GImmunoglobulin MCLIAcoccidioidomycosisdiagnosticenzyme immunoassaymonoclonal antibodies

Identifiers

PMID36121238
PMCPMC9602258
OpenAlexW4296330206

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.