Evidence map›Paper›PMID 36121169›Full record

ArticlemSystems2022

Dynamics of the Gut Microbiome in

Esther Ndungo, Johanna B Holm, Syze Gama, Andrea G Buchwald, Sharon M Tennant, Miriam K Laufer, Marcela F Pasetti, David A Rasko

Open access · goldAbstract read
In one paragraph

Article in mSystems, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed, 2 pooled it
1.3field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 2 syntheses or guidelines pooled it, 19 citations in OpenAlex.

  1. Burden ofBMJ global health · 2026
    Pooled it
  2. Consequences of Shigella infection in young children: a systematic review.International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases · 2023
    Pooled it
  3. Review
  4. Review
  5. Bacteriophage Therapy AgainstAntibiotics (Basel, Switzerland) · 2026
    Review
  6. Article
  7. Fecal microbiome profiling of children withMicrobiology spectrum · 2025
    Article
  8. Review
  9. Review
  10. Article
  11. Article
  12. Review
  13. Review
  14. Article
  15. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 2 countries.

Esther NdungoCenter for Vaccine Development and Global Health, University of Maryland School of Medicine, Baltimore, Maryland, USA.ORCID 0000-0002-9975-7032
Johanna B HolmInstitute for Genome Sciences, University of Maryland School of Medicine, Baltimore, Maryland, USA.ORCID 0000-0002-7646-4085
Syze GamaBlantyre Malaria Project, University of Malawi College of Medicine, Blantyre, Malawi.
Andrea G BuchwaldCenter for Vaccine Development and Global Health, University of Maryland School of Medicine, Baltimore, Maryland, USA.
Sharon M TennantCenter for Vaccine Development and Global Health, University of Maryland School of Medicine, Baltimore, Maryland, USA.ORCID 0000-0002-0651-5748
Miriam K LauferCenter for Vaccine Development and Global Health, University of Maryland School of Medicine, Baltimore, Maryland, USA.ORCID 0000-0001-8300-9593
Marcela F PasettiCenter for Vaccine Development and Global Health, University of Maryland School of Medicine, Baltimore, Maryland, USA.ORCID 0000-0003-0894-4009
David A RaskoInstitute for Genome Sciences, University of Maryland School of Medicine, Baltimore, Maryland, USA.ORCID 0000-0002-7337-7154
University of Maryland, Baltimore · USUniversity of Malawi · MW

Funding

QAQC Johns Hopkins Institute for Clinical and Translational ResearchUL1TR003098 · NCATS · JOHNS HOPKINS UNIVERSITY · PI FORD, DANIEL ERNEST · 2019 to 2023
$57.7M
Technology CoreU19AI110820 · NIAID · UNIVERSITY OF MARYLAND BALTIMORE · PI FRASER, CLAIRE M., RASKO, DAVID A · 2014 to 2023
$36.5M
Research Training in Gastroenterology and HepatologyT32DK067872 · NIDDK · UNIVERSITY OF MARYLAND BALTIMORE · PI RAUFMAN, JEAN-PIERRE · 2005 to 2024
$7.2M
Serological assays to predict Shigella vaccine efficacyR01AI125841 · NIAID · UNIVERSITY OF MARYLAND BALTIMORE · PI PASETTI, MARCELA F · 2016 to 2020
$2.8M
Vaccines and maternally acquired immunity to prevent shigellosis in childrenR01AI117734 · NIAID · UNIVERSITY OF MARYLAND BALTIMORE · PI PASETTI, MARCELA F · 2015 to 2019
$2.0M
HHS | NIH | National Center for Advancing Translational Sciences (NCATS) 1UL1TR003098HHS | NIH | National Institute of Allergy and Infectious Diseases (NIAID) R01AI117734HHS | NIH | National Institute of Allergy and Infectious Diseases (NIAID) U19AI110820HHS | NIH | National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) T32DK067872NCATS NIH HHS UL1 TR003098NIAID NIH HHS R01 AI117734NIAID NIH HHS R01 AI125841NIAID NIH HHS U19 AI110820NIDDK NIH HHS T32 DK067872
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Dysentery, BacillaryGastrointestinal MicrobiomeShigellaChildChild, PreschoolDiarrheaFecesHumansInfantQuality of LifeRNA, Ribosomal, 16SRNA, Ribosomal, 16Sgut microbiomeinfant microbiomeShigella

Identifiers

PMID36121169
PMCPMC9600951
OpenAlexW4296324333

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.