Evidence map›Paper›PMID 36120582›Full record

ArticleFrontiers in cell and developmental biology2022

Inhibiting DNA methylation as a strategy to enhance adipose-derived stem cells differentiation: Focus on the role of Akt/mTOR and Wnt/β-catenin pathways on adipogenesis.

S Ceccarelli, G Gerini, F Megiorni, P Pontecorvi, E Messina, S Camero, E Anastasiadou, E Romano, M G Onesti, C Napoli and 1 more

Open access · goldAbstract read
In one paragraph

Article in Frontiers in cell and developmental biology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
2.3field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 16 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Review
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 2 institutions in 1 country.

S CeccarelliDepartment of Experimental Medicine, Sapienza University of Rome, Rome, Italy.
G GeriniDepartment of Experimental Medicine, Sapienza University of Rome, Rome, Italy.
F MegiorniDepartment of Experimental Medicine, Sapienza University of Rome, Rome, Italy.
P PontecorviDepartment of Experimental Medicine, Sapienza University of Rome, Rome, Italy.
E MessinaDepartment of Experimental Medicine, Sapienza University of Rome, Rome, Italy.
S CameroDepartment of Maternal, Infantile and Urological Sciences, Sapienza University of Rome, Rome, Italy.
E AnastasiadouDepartment of Experimental Medicine, Sapienza University of Rome, Rome, Italy.
E RomanoDepartment of Sense Organs, Sapienza University of Rome, Rome, Italy.
M G OnestiDepartment of Surgery "P. Valdoni", Unit of Plastic Surgery "P. Valdoni", Sapienza University of Rome, Rome, Italy.
C NapoliDepartment of Advanced Medical and Surgical Sciences (DAMSS), University of Campania "Luigi Vanvitelli", Naples, Italy.
C MarcheseDepartment of Experimental Medicine, Sapienza University of Rome, Rome, Italy.
Sapienza University of Rome · ITUniversity of Campania "Luigi Vanvitelli" · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Adipose-derived mesenchymal stem cells (ASCs) represent a valid therapeutic option for clinical application in several diseases, due to their ability to repair damaged tissues and to mitigate the inflammatory/immune response. A better understanding of the underlying mechanisms regulating ASC biology might represent the chance to modulate their

Indexed as

5-azacytidineadipogenesisadipose-derived adult stem cells (ASCs)AKT/mTORepigenetic regulationWnt/ beta-catenin pathway

Identifiers

PMID36120582
PMCPMC9478209
OpenAlexW4294168554

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.