Evidence map›Paper›PMID 36120475›Full record

ArticlemicroPublication biology2022

Oocyte CTR1 is not essential for cisplatin-induced oocyte death of primordial follicle.

Seok-Yeong Yu, Yi Luan, Amirhossein Abazarikia, Rosemary Dong, Jaekwon Lee, So-Youn Kim

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in microPublication biology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.6field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 3 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Seok-Yeong YuOlson Center for Women's Health, Department of Obstetrics and Gynecology, College of Medicine, University of Nebraska Medical Center, Omaha, NE.
Yi LuanOlson Center for Women's Health, Department of Obstetrics and Gynecology, College of Medicine, University of Nebraska Medical Center, Omaha, NE.
Amirhossein AbazarikiaOlson Center for Women's Health, Department of Obstetrics and Gynecology, College of Medicine, University of Nebraska Medical Center, Omaha, NE.
Rosemary DongOlson Center for Women's Health, Department of Obstetrics and Gynecology, College of Medicine, University of Nebraska Medical Center, Omaha, NE.
Jaekwon LeeDepartment of Biochemistry, University of Nebraska, Lincoln, Nebraska, USA.
So-Youn KimOlson Center for Women's Health, Department of Obstetrics and Gynecology, College of Medicine, University of Nebraska Medical Center, Omaha, NE.
University of Nebraska–Lincoln · US

Funding

Development of mechanism-based ovarian reserve protecting adjuvant therapies against gonadotoxic therapeutic agentsR01HD096042 · NICHD · UNIVERSITY OF NEBRASKA MEDICAL CENTER · PI KIM, SO-YOUN · 2019 to 2023
$1.6M
NICHD NIH HHS R01 HD096042
6 · The paper itself

Abstract

Accumulated evidence indicates that cisplatin, a platinum-based alkylating agent, causes preferential DNA damage to oocytes of primordial follicles (PFs) in the ovary, suggesting oocyte-favored accumulation of cisplatin. Copper transporter 1 (CTR1;

Identifiers

PMID36120475
PMCPMC9478746
OpenAlexW4296327412

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.