Evidence map›Paper›PMID 36120419›Full record

ArticleEuropean urology open science2022

"Light green up": Indocyanine Green Fluorescence Imaging-guided Robotic Bilateral Inguinal Lymphadenectomy by the Hypogastric Subcutaneous Approach for Penile Cancer.

Peng Yuan, Kun Yao, Zhijiao Zhou, Jianye Liu, Chao Li, Weibin Hou, Yongxiang Tang, Shuo Hu, Long Wang

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in European urology open science, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed, 2 pooled it
1.5field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 2 syntheses or guidelines pooled it, 8 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Peng YuanDepartment of Urology, The Third Xiangya Hospital, Central South University, Changsha, Hunan, China.
Kun YaoDepartment of Urology, The Third Xiangya Hospital, Central South University, Changsha, Hunan, China.
Zhijiao ZhouDepartment of Pathology, The Third Xiangya Hospital, Central South University, Changsha, Hunan, China.
Jianye LiuDepartment of Urology, The Third Xiangya Hospital, Central South University, Changsha, Hunan, China.
Chao LiDepartment of Urology, The Third Xiangya Hospital, Central South University, Changsha, Hunan, China.
Weibin HouDepartment of Urology, The Third Xiangya Hospital, Central South University, Changsha, Hunan, China.
Yongxiang TangDepartment of Nuclear Medicine, Xiangya Hospital, Central South University, Changsha, Hunan, China.
Shuo HuDepartment of Nuclear Medicine, Xiangya Hospital, Central South University, Changsha, Hunan, China.
Long WangDepartment of Urology, The Third Xiangya Hospital, Central South University, Changsha, Hunan, China.
Central South University · CNThird Xiangya Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Inguinal lymphadenectomy is of great significance in the management of penile cancer, which aims to mitigate the progression of lymph node metastasis. It is important to improve the efficiency of lymph node dissection and reduce surgical complications. Objective: To detail a novel technique for robotic bilateral inguinal lymphadenectomy through the hypogastric subcutaneous approach by indocyanine green (ICG) fluorescence imaging, which promotes the identification and dissection of inguinal lymph nodes with considerable safety. Design setting and participants: Ten eligible penile cancer patients who underwent ICG fluorescence imaging-guided robotic bilateral inguinal lymphadenectomy were prospectively enrolled (ICG group). Sixteen patients who underwent the surgery without ICG were retrospectively set as the control (non-ICG) group. Follow-up records for at least 12 mo were required. Surgical procedure: Inguinal lymphadenectomy was performed by the hypogastric subcutaneous approach. The ICG solution was subcutaneously injected into the prepuce at the beginning of surgery, and ICG fluorescence imaging-guided robotic-assisted bilateral inguinal lymphadenectomy was conducted. Measurements: Clinical outcomes were collected. The primary study outcome measurement was the number of dissected inguinal lymph nodes. Results and limitations: The numbers of inguinal overall, superficial, and deep lymph nodes retrieved were all higher in the ICG than in the non-ICG group ( Conclusions: ICG fluorescence imaging-guided robotic inguinal lymphadenectomy via the hypogastric subcutaneous approach is feasible and safe for patients with penile cancer, which is beneficial for dissecting more inguinal lymph nodes with few surgical complications. Patient summary: We developed a promising indocyanine green fluorescence imaging-guided technique to perform robotic bilateral inguinal lymphadenectomy on patients with penile cancer, which conduces to remove more inguinal lymph nodes with limited complications.

Indexed as

Fluorescence imagingIndocyanine greenInguinal lymphadenectomyPenile cancer

Identifiers

PMID36120419
PMCPMC9478926
OpenAlexW4295630583

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.