Evidence map›Paper›PMID 36120231›Full record

ReviewCureus2022

COVID-19 Vaccine Clinical Trials: A Bird's Eye Perspective.

Pujitha Vallivedu Chennakesavulu, Gaurav Venkat Cuddapah, Mayura Reddy Keesara, Jyothik Varun Inampudi, Amulya Arremsetty, Sushma Moka, Swamy Miryala

Abstract readReview
In one paragraph

Review in Cureus, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Pujitha Vallivedu ChennakesavuluInternal Medicine, Kamineni Academy of Medical Sciences and Research Centre, Hyderabad, IND.
Gaurav Venkat CuddapahInternal Medicine, Kamineni Academy of Medical Sciences and Research Centre, Hyderabad, IND.
Mayura Reddy KeesaraInternal Medicine, Apollo Institute of Medical Sciences and Research, Hyderabad, IND.
Jyothik Varun InampudiInternal Medicine, Siddhartha Medical College, Vijayawada, IND.
Amulya ArremsettyInternal Medicine, Siddhartha Medical College, Vijayawada, IND.
Sushma MokaInternal Medicine, Kamineni Academy of Medical Sciences and Research Centre, Hyderabad, IND.
Swamy MiryalaInternal Medicine, Kamineni Academy of Medical Sciences and Research Centre, Hyderabad, IND.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Several Phase-III clinical studies investigating vaccine safety and effectiveness have been published a year following the first breakout of the COVID-19 pandemic. These vaccine candidates were produced using a variety of vaccination technologies, including mRNA, recombinant protein, adenoviral vector, and inactivated virus-based platforms, by various research organizations and pharmaceutical firms. Despite many successful clinical studies, participants are restricted by trial inclusion and exclusion criteria, geographic location, and the current state of the virus epidemic. Many concerns remain, particularly for specific populations such as the elderly, women who are pregnant or nursing, and teenagers. Vaccine effectiveness against asymptomatic infection and particular viral variations, on the other hand, is still largely unclear. This review will focus on vaccination candidates that have completed Phase-III clinical trials and will examine the scientific evidence that has been gathered so far for these vaccine candidates for various subgroups of individuals and virus variations.

Indexed as

clinical trials in all phases (i-iv)covid 19covid-19 vaccinecovid-2019infectious and tropical diseasespreventive healthsars-cov-2severe acute respiratory syndrome coronavirus-2 (sars-cov-2)

Identifiers

PMID36120231
PMCPMC9477158

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.