ArticleJournal of inflammation research2022
Systemic Immune-Inflammation Index Predicts Long-Term Outcomes in Patients with Three-Vessel Coronary Disease After Revascularization: Results from a Large Cohort of 3561 Patients.
Article in Journal of inflammation research, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 1 of them a synthesis that pooled it.
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Who cites it
22 citing papers in PubMed, 1 synthesis or guideline pooled it, 24 citations in OpenAlex.
- Systemic immune inflammation index with all-cause and cause-specific mortality: a meta-analysis.Inflammation research : official journal of the European Histamine Research Society ... [et al.] · 2024Pooled it
- Predictive Value of the Systemic Immune-Inflammation Index for Cardiovascular Events in Patients With Chronic Total Coronary Occlusion.Reviews in cardiovascular medicine · 2026Article
- Research status and hotspots of the systemic immune-inflammation index: A bibliometric analysis.Medicine · 2026Article
- Prognostic Value of Systemic Immune-Inflammation Index (SII) in Hospital Readmission Following Acute Myocardial Infarction: A Four-Year Analysis.Cardiology research and practice · 2026Article
- Association between systemic immune-inflammation index and ventricular premature contractions in patients without structural heart disease.Frontiers in cardiovascular medicine · 2026Article
- Systemic immune-inflammation Index is an independent risk factor for Major adverse cardiovascular events in patients with coronary artery ectasia.Frontiers in cardiovascular medicine · 2026Article
- Association between single-point insulin sensitivity estimator and three-vessel coronary disease: a cross-sectional study.Frontiers in endocrinology · 2026Article
- The systemic immune-inflammation index in coronary heart disease: a narrative review of thromboinflammation, phenotype-dependent utility, and clinical translation.Frontiers in cardiovascular medicine · 2026Review
- C-reactive protein-triglyceride glucose index in predicting three-vessel coronary artery disease risk: a retrospective study using machine learning approaches.Annals of medicine · 2025Article
- Inflammation-Based Hematologic Indices as Prognostic Markers in Pulmonary Arterial and Chronic Thromboembolic Pulmonary Hypertension: A Hypothesis-Generating Registry Study.International journal of molecular sciences · 2025Article
- Prognostic value of systemic immune-Inflammatory index in patients with diabetes mellitus and acute coronary syndrome after percutaneous coronary intervention: a prospective cohort study.BMC cardiovascular disorders · 2025Article
- Combining triglyceride glucose-body mass index and high-sensitivity C-reactive protein to predict cardiovascular disease: results from a national cohort and a clinical verified cohort.Frontiers in cardiovascular medicine · 2025Article
- Association and Comparison of Systemic Inflammation Indicators and Myocardial Injury After Noncardiac Surgery in Older Patients.Journal of inflammation research · 2025Article
- The Predictive and Prognostic Value of the Systemic Immune-Inflammation Index for Congestive Heart Failure.Reviews in cardiovascular medicine · 2024Article
- Prognosis impact of multiple novel lymphocyte-based inflammatory indices in patients with initially diagnosed coronary artery disease.Immunity, inflammation and disease · 2024Article
- Prenatal and childhood air pollution exposure, cellular immune biomarkers, and brain connectivity in early adolescents.Brain, behavior, & immunity - health · 2024Article
- Article
- The Predictive Value of the Systemic Immune-Inflammation Index for Cardiovascular Events in Chronic Total Occlusion Patients Who Prior Coronary Artery Bypass Grafting.Journal of inflammation research · 2024Article
- Significance of Multiple Lymphocyte-to-C-Reactive Protein Ratios in Predicting Long-Term Major Cardiovascular Adverse Events in Emergency Percutaneous Coronary Intervention Patients with ST-Segment Elevation Myocardial Infarction.Journal of inflammation research · 2024Article
- Predictive value of high sensitivity C-reactive protein in three-vessel disease patients with and without type 2 diabetes.Cardiovascular diabetology · 2023Article
Corrections and comments
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Authors and funding
7 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Objective: This study aimed to investigate the prognostic value of systemic immune inflammation index (SII) concerning long-term outcomes in patients with the three-vessel disease (TVD) after revascularization in a large cohort. Methods: In total, 3561 TVD patients who had undergone revascularization between 2013 and 2018 were included in the study. Patients were divided into the low SII (<694.3 × 10 Results: After 2.4 years of follow-up, the Cox proportional hazard regression model analysis displayed that high SII was independently associated with an increased risk of developing future MACCE (hazard ratio [HR] 1.65, 95% confidence interval [CI] 1.23-2.21, p = 0.001) and all-cause death (HR: 2.96; 95% CI: 1.19-7.32, p = 0.019). The addition of SII significantly improved the reclassification beyond the baseline model with traditional risk factors (MACCE: NRI, 0.115; p = 0.0001; all-cause death: NRI, 0.369; p = 0.0001). Reclassification with the addition of SII also demonstrated an IDI of 0.0022 (p = 0.006) in MACCE and 0.0033 (p = 0.014) in all-cause death. Conclusion: In TVD patients after revascularization, increased SII is an independent prognostic factor for long-term outcomes of MACCE and death. Compared to traditional risk factors, SII improved the risk prediction of major cardiovascular events in TVD patients who underwent revascularization.
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Registered trials
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