Evidence map›Paper›PMID 36120106›Full record

ArticleAddiction neuroscience2022

The subjective experience of heroin effects among individuals with chronic opioid use: Revisiting reinforcement in an exploratory study.

Suky Martinez, Laura Brandt, Sandra D Comer, Frances R Levin, Jermaine D Jones

Open access · goldAbstract read
In one paragraph

Article in Addiction neuroscience, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.8field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 8 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Review
  5. Review
  6. The influence of drug class on reward in substance use disorders.Pharmacology, biochemistry, and behavior · 2024
    Review
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Suky MartinezDivision on Substance Use Disorders, Columbia University Irving Medical Center & New York State Psychiatric Institute, 1051 Riverside Drive, New York, NY 10032, United States of America.
Laura BrandtDivision on Substance Use Disorders, Columbia University Irving Medical Center & New York State Psychiatric Institute, 1051 Riverside Drive, New York, NY 10032, United States of America.
Sandra D ComerDivision on Substance Use Disorders, Columbia University Irving Medical Center & New York State Psychiatric Institute, 1051 Riverside Drive, New York, NY 10032, United States of America.
Frances R LevinDivision on Substance Use Disorders, Columbia University Irving Medical Center & New York State Psychiatric Institute, 1051 Riverside Drive, New York, NY 10032, United States of America.
Jermaine D JonesDivision on Substance Use Disorders, Columbia University Irving Medical Center & New York State Psychiatric Institute, 1051 Riverside Drive, New York, NY 10032, United States of America.
Columbia University · US

Funding

Translational Clinical Research Fellowship on Substance Use DisordersT32DA007294 · NIDA · COLUMBIA UNIV NEW YORK MORNINGSIDE · PI Frances Rudnick Levin, Diana M Martinez · 1993 to 2026
$9.3M
Translational Research Training on Addictions for Racial/Ethnic MinoritiesR25DA035161 · NIDA · CITY COLLEGE OF NEW YORK · PI DENISE AIMEE HIEN, Lesia Monique Ruglass · 2013 to 2026
$4.4M
Risk and Benefits of Overdose Education and Naloxone Prescribing to Heroin UsersR01DA035207 · NIDA · NEW YORK STATE PSYCHIATRIC INSTITUTE DBA RESEARCH FOUNDATION FOR MENTAL HYGIENE, INC · PI COMER, SANDRA D · 2014 to 2018
$2.7M
Assessing the effects of heroin use on epigenetic agingR21DA043199 · NIDA · NEW YORK STATE PSYCHIATRIC INSTITUTE DBA RESEARCH FOUNDATION FOR MENTAL HYGIENE, INC · PI JONES, JERMAINE D · 2018 to 2019
$446k
NIDA NIH HHS R01 DA035207NIDA NIH HHS R21 DA043199NIDA NIH HHS R25 DA035161NIDA NIH HHS T32 DA007294
6 · The paper itself

Abstract

Aims: Consistent with the opponent process theory individuals with chronic opioid use should predominantly endorse the avoidance of aversive negative emotional and/or physiological states as the motivation for continued opioid use (source of reinforcement: reductions in negative states). The primary aim of this study was to explore whether this view is supported by the subjective effects of heroin reported by individuals with opioid use disorder (OUD). Methods: Responses during in-person interviews of participants to the question "What do you like about heroin? " were categorized as positive, negative, or mixed (positive and negative) reinforcement. In addition, we examined differences between these "reinforcement groups" in sociodemographic and clinical variables. Results: Participants ( Conclusions: The results of this study indicate marked heterogeneity of heroin effects experienced by individuals with OUD and their source of reinforcement, respectively. Better integration of how individuals construe their drug use is important to understand the psychological-and neurobiological-processes in the development and maintenance of OUD.

Indexed as

HeroinHeterogeneityReinforcementSubjective experienceSurrogate measure

Identifiers

PMID36120106
PMCPMC9481059
OpenAlexW4293382957

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.