Evidence map›Paper›PMID 36120001›Full record

ArticleACS omega2022

Autoclaving pHEMA-Based Hydrogels Immersed in Deionized Water has No Effect on Physicochemical Properties and Cell Behaviors.

Wanliu Peng, Xingbing Lu, Junliang Wu, Yi Wang, Xinglong Zhu, Hongyan Ouyang, Li Li, Jinrong Wu, Yong Liu, Ji Bao

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in ACS omega, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.6field-weighted citation impact, top 39% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 7 citations in OpenAlex.

  1. Review
  2. Review
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

Wanliu PengInstitute of Clinical Pathology, Key Laboratory of Transplant Engineering and Immunology, NHC, West China Hospital, Sichuan University, Chengdu 610041, Sichuan Province, China.
Xingbing LuDepartment of Laboratory Medicine, West China Hospital, Sichuan University, Chengdu 610041, Sichuan Province, China.
Junliang WuDepartment of Plastic and Burn Surgery, West China Hospital, Sichuan University, Chengdu 610041, Sichuan Province, China.
Yi WangCollege of Chemistry and Materials Science, Sichuan Normal University, Chengdu 610068, Sichuan Province, China.
Xinglong ZhuInstitute of Clinical Pathology, Key Laboratory of Transplant Engineering and Immunology, NHC, West China Hospital, Sichuan University, Chengdu 610041, Sichuan Province, China.
Hongyan OuyangCollege of Chemistry and Materials Science, Sichuan Normal University, Chengdu 610068, Sichuan Province, China.
Li LiInstitute of Clinical Pathology, West China Hospital, Sichuan University, Chengdu 610041, Sichuan Province, China.
Jinrong WuCollege of Polymer Science & Materials, State Key Laboratory of Polymer Materials Engineering, Sichuan University, Chengdu 610065, Sichuan Province, China.ORCID https://orcid.org/0000-0002-5329-5522
Yong LiuDepartment of Plastic and Burn Surgery, West China Hospital, Sichuan University, Chengdu 610041, Sichuan Province, China.
Ji BaoInstitute of Clinical Pathology, Key Laboratory of Transplant Engineering and Immunology, NHC, West China Hospital, Sichuan University, Chengdu 610041, Sichuan Province, China.ORCID https://orcid.org/0000-0001-8413-3270
Sichuan University · CNSichuan Normal University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Hydrogels based on poly-(2-hydroxyethyl methacrylate) (pHEMA) have been widely used as biomaterials in tissue engineering due to their biocompatibility, hydrophilicity, and low friction coefficient. The terminal sterilization of hydrogels is a critical step in clinical applications. However, regulations and standardization for the sterilization of hydrogels based on pHEMA are still lacking. In this study, we explored six sterilization methods on pHEMA-based materials (A1: pHEMA, A2: pHEMA copolymerizes with acrylic acid, and A3: pHEMA copolymerizes with acrylic acid and further coordinated with iron ions), such as gamma irradiation, 75% ethanol, ultraviolet (UV), ethylene oxide (EtO), and autoclaving with or without deionized water (autoclaving-H

Identifiers

PMID36120001
PMCPMC9475621
OpenAlexW4293704133

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.