Evidence map›Paper›PMID 36119799›Full record

ReviewChinese herbal medicines2020

Immunomodulatory effects and structure-activity relationship of botanical pentacyclic triterpenes: A review.

Nurul Hikmah Harun, Abdi Wira Septama, Wan Amir Nizam Wan Ahmad, Rapeah Suppian

Abstract readReview
In one paragraph

Review in Chinese herbal medicines, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed.

  1. Article
  2. Article
  3. Immunoenhancing Effects of JejuPharmaceuticals (Basel, Switzerland) · 2025
    Article
  4. Article
  5. Advances in pharmacological and pharmaceutical sciences · 2025
    Article
  6. Article
  7. Article
  8. Article
  9. Review
  10. Bioactivity of the GenusPharmaceuticals (Basel, Switzerland) · 2023
    Review
  11. Article
  12. Review
  13. Review
  14. Article
  15. Immunomodulatory properties of triterpenes.Phytochemistry reviews : proceedings of the Phytochemical Society of Europe · 2022
    Review
  16. Review
  17. Anticancer Potential of Betulonic Acid Derivatives.International journal of molecular sciences · 2021
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Nurul Hikmah HarunSchool of Health Sciences, Heath Campus, Universiti Sains Malaysia, Kubang Kerian 16150, Malaysia.
Abdi Wira SeptamaResearch Center for Chemistry, Indonesian Institute of Sciences, Kawasan Puspitek Serpong, Tangerang Selatan 15314, Indonesia.
Wan Amir Nizam Wan AhmadSchool of Health Sciences, Heath Campus, Universiti Sains Malaysia, Kubang Kerian 16150, Malaysia.
Rapeah SuppianSchool of Health Sciences, Heath Campus, Universiti Sains Malaysia, Kubang Kerian 16150, Malaysia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Botanical pentacyclic triterpenes possessed a broad range of pharmacological activities such as anti-oxidant, anti-tumor, anti-microbial and anti-inflammatory activities. It is believed that the mechanisms involved in these bioactivities are due to the modulation of immune system. Recently, the pharmacological validation on immunomodulatory of pentacyclic triterpenes derived from higher plants is very limited and several existence review papers related for this group of compound have not been focused for this activity. In this review, we have highlighted several studies on immunomodulatory potential of botanical pentacyclic triterpenes isolated from wide array of different species of medicinal plants and herbs based on various preclinical

Indexed as

botanicalimmunomodulatorypentacyclic triterpenesstructure activity relationship

Identifiers

PMID36119799
PMCPMC9476727

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.