ArticleFrontiers in neurology2022
Global, regional, and national neck pain burden in the general population, 1990-2019: An analysis of the global burden of disease study 2019.
Article in Frontiers in neurology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 68 papers, 7 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
68 citing papers in PubMed, 7 syntheses or guidelines pooled it.
- The effects of physiotherapy on neck pain with associated symptoms, ıncludıng cervicogenic dizziness and tinnitus: a systematic review.BMC musculoskeletal disorders · 2026Pooled it
- Cervical disc replacement versus anterior cervical discectomy and fusion using stand-alone cage for degenerative cervical spondylosis: a systematic review and meta-analysis based on randomized controlled trials.Neurosurgical review · 2025Pooled it
- Exercise and Heart Rate Variability in Chronic Musculoskeletal Pain: A Systematic Review.Sports medicine - open · 2025Pooled it
- Comparative effectiveness of six biophysical agents on neck pain rehabilitation: a systematic review and network meta-analysis.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2025Pooled it
- The Analgesic Potential of Litsea Species: A Systematic Review.Molecules (Basel, Switzerland) · 2024Pooled it
- Does manual therapy meaningfully change quantitative sensory testing and patient reported outcome measures in patients with musculoskeletal impairments related to the spine?: A 'trustworthy' systematic review and meta-analysis.The Journal of manual & manipulative therapy · 2024Pooled it
- Self-locking stand-alone cage versus cage-plate fixation in monosegmental anterior cervical discectomy and fusion with a minimum 2-year follow-up: a systematic review and meta-analysis.Journal of orthopaedic surgery and research · 2023Pooled it
- Comparison of Traditional Chinese Manual Therapy (Tuina) and Extracorporeal Shock Wave Therapy in Patients With Nonspecific Neck Pain: Protocol for a Randomized Controlled Trial.JMIR research protocols · 2026Trial
- Effects Of 6-Week Telerehabilitation Exercise Programme On Chronic Non-Specific Neck Pain In Women: A Pilot Randomized Controlled Trial.F1000Research · 2025Trial
- A Randomized Control Trial of Dexketoprofen/Vitamin B (Thiamine, Pyridoxine and Cyanocobalamin) Fixed-Dose Combination in Post-Traumatic Grade I-II Cervical Sprains.Clinical drug investigation · 2024Trial
- Trial
- The Reliability of Biomechanical Mensuration Methods of the Sagittal Cervical Spine in Radiography Used in Clinical Practice: A Systematic Review of the Literature.Journal of clinical medicine · 2026Review
- Cognitive-behavioural treatment for neck pain.The Cochrane database of systematic reviews · 2026Article
- Elastographic Changes in Cervical Muscle Following Combined Radial Extracorporeal Shockwave Therapy and Orthopedic Manual Therapy: A Randomized Controlled Trial.Journal of clinical medicine · 2026Article
- [Analysis of current status and trends of disease burden of neck pain in China from 1990 to 2023].Zhongguo xiu fu chong jian wai ke za zhi = Zhongguo xiufu chongjian waike zazhi = Chinese journal of reparative and reconstructive surgery · 2026Article
- Examining the association between neck pain and depressive symptoms in middle-aged and older Chinese adults: findings from the China Health and Retirement Longitudinal Study (CHARLS).BMC public health · 2026Article
- Increased Cervical Disc Height and Decreased Neck Pain and Disability Following Improvement in Cervical Lordosis and Posture Using Chiropractic BioPhysics.Bioengineering (Basel, Switzerland) · 2026Article
- Improvement in Cervical Spinal Alignment and Posture May Redefine Recovery Pathways for Motor Vehicle Collision Whiplash Injury: A Multicenter Retrospective Consecutive Case Series.Healthcare (Basel, Switzerland) · 2026Article
- Upper Extremity Neurovascular Injuries in Collegiate Athletes: Sex, Race, and Return to Sport.Orthopaedic journal of sports medicine · 2026Article
- Acupotomy Activates PI3K/Akt Signaling Pathway Mediated by FGF7,10/KDR Axis to Regulate Apoptosis.Journal of pain research · 2026Article
8 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: This study describes the global epidemiology and trends associated with neck pain. Global Burden of Disease data collected between 1990 and 2019 were used to determine the global burden of neck pain in the general populations of 204 countries. Methods: Global, regional, and national burdens of neck pain determined by prevalence, incidence, and years lived with a disability (YLD) from 1990 to 2019 were comprehensively analyzed according to age, gender, and socio-demographic index using the Global Burden of Disease Study 1990 and 2019 data provided by the Institute for Health Metrics and Evaluation. Results: Globally, in 2019, the age-standardized rates for prevalence, incidence, and YLD of neck pain per 100,000 population was 2,696.5 (95% uncertainty interval [UI], 2,177.0 to 3,375.2), 579.1 (95% UI, 457.9 to 729.6), and 267.4 (95% UI, 175.5 to 383.5) per 100,000 population, respectively. Overall, there was no significant difference in prevalence, incidence, or YLD of neck pain between 1990 and 2019. The highest age-standardized YLD of neck pain per 100,000 population in 2019 was observed in high-income North America (479.1, 95% UI 323.0 to 677.6), Southeast Asia (416.1, 95% UI 273.7 to 596.5), and East Asia (356.4, 95% UI 233.2 to 513.2). High-income North America (17.0, 95% UI 9.0 to 25.4%) had the largest increases in YLD of neck pain per 100,000 population from 1990 to 2019. At the national level, the highest age-standardized YLD of neck pain was found in the Philippines (530.1, 95% UI 350.6 to 764.8) and the highest change age-standardized YLD between 1990 and 2019 was found in the United States (18.4, 95% UI 9.9 to 27.6%). Overall, the global burden of neck pain increased with age until the age of 70-74 years, and was higher in women than men. In general, positive associations between socio-demographic index and burden of neck pain were found. Conclusions: Because neck pain is a major public health burden with a high prevalence, incidence, and YLD worldwide, it is important to update its epidemiological data and trends to cope with the future burden of neck pain.
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