Evidence map›Paper›PMID 36119659›Full record

ArticleThe World Allergy Organization journal2022

Mollusk allergy in shrimp-allergic patients: Still a complex diagnosis. An Italian real-life cross-sectional multicenter study.

Enrico Scala, Damiano Abeni, Arianna Aruanno, Elisa Boni, Ignazio Brusca, Francesca Cappiello, Elisabetta Caprini, Francesca Buzzulini, Gaia Deleonardi, Antongiulio Demonte and 22 more

Open access · goldAbstract read
In one paragraph

Article in The World Allergy Organization journal, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.3field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 10 citations in OpenAlex.

  1. Review
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  3. Article
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

32 authors at 13 institutions in 1 country.

Enrico ScalaClinical and Laboratory Molecular Allergy Unit - IDI-IRCCS | FLMM, Roma, Italy.
Damiano AbeniClinical and Laboratory Molecular Allergy Unit - IDI-IRCCS | FLMM, Roma, Italy.
Arianna AruannoFondazione Policlinico Universitario A. Gemelli IRCCS, Università Cattolica del Sacro Cuore, Roma, Italy.
Elisa BoniAllergologia e autoimmunità LUM AUSL, Bologna, Italy.
Ignazio BruscaClinical Pathology U.O.C., Buccheri La Ferla F.B.F. Hospital, Palermo, Italy.
Francesca CappielloAllergy Unit ASST Lecco and Merate, Italy.
Elisabetta CapriniClinical and Laboratory Molecular Allergy Unit - IDI-IRCCS | FLMM, Roma, Italy.
Francesca BuzzuliniSSD di immunologia e Allergologia, PO S. Maria Degli Angeli, Pordenone, Italy.
Gaia DeleonardiAllergologia e autoimmunità LUM AUSL Bologna, Italy.
Antongiulio DemonteUOsD Allergologia, ospedale G. Da Saliceto, Piacenza, Italy.
Laura FarioliDipartimento di Allergologia, ASST Grande Ospedale Metropolitano Niguarda, Milano, Italy.
Fabio Lodi RizziniSSVD Allergologia Spedali Civili - Università Studi Brescia, Brescia, Italy.
Laura Michelina LosappioDipartimento di Allergologia, ASST Grande Ospedale Metropolitano Niguarda, Milano, Italy.
Donatella MacchiaSOS Allergologia e Immunologia Clinica, Ospedale San Giovanni di Dio, Firenze, Italy.
Giuseppina ManzottiServizio di Allergologia, Casa di Cura Beato Palazzolo, Bergamo, Italy.
Giorgia MeneguzziClinical and Laboratory Molecular Allergy Unit - IDI-IRCCS | FLMM, Roma, Italy.
Marcello MontagniUOsD Allergologia, ospedale G. Da Saliceto, Piacenza, Italy.
Eleonora NuceraFondazione Policlinico Universitario A. Gemelli IRCCS, Università Cattolica del Sacro Cuore, Roma, Italy.
Rosa OnidaClinical Pathology U.O.C., Buccheri La Ferla F.B.F. Hospital, Palermo, Italy.
Elide Anna PastorelloDipartimento di Allergologia, ASST Grande Ospedale Metropolitano Niguarda, Milano, Italy.
Silvia PeveriUOsD Allergologia, ospedale G. Da Saliceto, Piacenza, Italy.
Anna RadiceSOS Allergologia e Immunologia Clinica, Ospedale San Giovanni di Dio, Firenze, Italy.
Federica RivoltaImmunology and Allergy Department, IRCCS Foundation Ca' Granda Ospedale Maggiore Policlinico, Milan, Italy.
Angela RizziFondazione Policlinico Universitario A. Gemelli IRCCS, Università Cattolica del Sacro Cuore, Roma, Italy.
Mauro GianiClinical and Laboratory Molecular Allergy Unit - IDI-IRCCS | FLMM, Roma, Italy.
Lorenzo CecchiSOS Allergology and Clinical Immunology, USL Toscana Centro, Prato, Italy.
Elena PinterUOC Medicina interna e Immunologia Clinica, Department of Molecular Medicine, Sapienza University of Rome, Rome, Italy.
Marzia MiglionicoDepartment of Molecular Medicine, Sapienza University of Rome, Rome, Italy.
Lorenzo VantaggioDepartment of Translational and Precision Medicine, Sapienza University of Rome, Italy.
Valerio PravettoniImmunology and Allergy Department, IRCCS Foundation Ca' Granda Ospedale Maggiore Policlinico, Milan, Italy.
Danilo VillaltaSSD di immunologia e Allergologia, PO S. Maria Degli Angeli, Pordenone, Italy.
Riccardo AseroAmbulatorio di allergologia, Clinica San Carlo, Paderno Dugnano (MI), Italy.
Istituti di Ricovero e Cura a Carattere Scientifico · ITAzienda Socio Sanitaria Territoriale Grande Ospedale Metropolitano Niguarda · ITGuglielmo da Saliceto Hospital · ITSapienza University of Rome · ITUniversità Cattolica del Sacro Cuore · ITAzienda Ospedaliera Santa Maria Degli Angeli · ITFondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico · ITNuovo Ospedale San Giovanni di Dio · ITOspedale Buccheri la Ferla Fatebenefratelli · ITAzienda Socio Sanitaria Territoriale degli Spedali Civili di Brescia · ITAzienda Usl Toscana Centro · ITAziende Socio Sanitarie Territoriali di LeccoOspedale San Carlo · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: Shellfish allergy is an important cause of food allergies worldwide. Both Aim: To investigate the features of shrimp-allergic patients either reactive or tolerant to mollusks, with the currently available diagnostic methods. Methods: Nineteen centers, scattered throughout Italy, participated in the real-life study, enrolling patients allergic to shrimp with or without associated reactions to mollusks. Patients underwent skin tests using commercial extracts or fresh raw and cooked shrimp and mollusks, and IgE reactivity to currently available allergenic extracts and molecules was measured Results: Two hundred and forty-seven individuals with a self reported adverse reactions to shrimp participated in the study; of these 47.8% reported an adverse reaction to mollusks ingestion (cephalopod and/or bivalve). Neither of the tests used, Conclusion: The current diagnostic methods are inadequate to predict the cross-reactivity between crustaceans and mollusks. The detection of mollusks hypersensitivity should still rely on skin tests with fresh material. The exclusion of mollusks from shrimp allergic patients' diets should occur when clinical history, available diagnostic instruments, and/or tolerance tests support such a decision.

Indexed as

AnaphylaxisCrustaceansFood allergyIgE diagnosisMollusksMultiplex analysisTropomyosinUrticaria/angioedema

Identifiers

PMID36119659
PMCPMC9468587
OpenAlexW4294612842

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.