Evidence map›Paper›PMID 36119655›Full record

ArticleThe World Allergy Organization journal2022

Efficacy and safety of subcutaneous immunotherapy with a mixture of glutaraldehyde-modified extracts of

Ricardo Cardona-Villa, Susana Uribe-Garcia, Víctor Daniel Calvo-Betancur, Jose Fernando Cantillo, Enrique Fernández-Caldas

Registry-linked trialOpen access · goldAbstract read
In one paragraph

Article in The World Allergy Organization journal, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07427576 (Retrospective Study Evaluating the Effectiveness and Safety of Immunotherapy With Clustoid®/Clustek®/Alxoid® for the Treatment of Dermatophagoides/Blomia Tropicalis Allergy in Real-Life Conditions), which is not on this map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
1.4field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07427576 completednot on this mapstarted 2025, after this paper: background citation

Retrospective Study Evaluating the Effectiveness and Safety of Immunotherapy With Clustoid®/Clustek®/Alxoid® for the Treatment of Dermatophagoides/Blomia Tropicalis Allergy in Real-Life Conditions

TypeobservationalSponsorInmunotek S.L.Ran2025 to 2025Enrolled140ConditionsMite Allergy, Dermatophagoides Farinae Allergy, Dermatophagoides Pteronyssinus Allergy, Rhinitis, AllergicArmsClustoid® Max Forte
3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 11 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Frequent IgE recognition ofFrontiers in immunology · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 3 countries.

Ricardo Cardona-VillaGrupo de Alergología Clínica y Experimental (GACE), University of Antioquia, Medellín, Antioquia, Colombia.
Susana Uribe-GarciaGrupo de Alergología Clínica y Experimental (GACE), University of Antioquia, Medellín, Antioquia, Colombia.
Víctor Daniel Calvo-BetancurGrupo de Alergología Clínica y Experimental (GACE), University of Antioquia, Medellín, Antioquia, Colombia.
Jose Fernando CantilloInmunotek, S.L. Alcalá de Henares, Madrid, Spain.
Enrique Fernández-CaldasInmunotek, S.L. Madrid and University of South Florida College of Medicine, Tampa, FL, USA.
Universidad de Antioquia · COInmunotek (Spain) · ESUniversity of South Florida · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Allergen Immunotherapy (AIT) is an effective treatment of allergic respiratory diseases induced by the inhalation of house dust mite allergens. Objectives: To evaluate the efficacy and safety of glutaraldehyde polymerized allergen extracts using a mixture of Methods: Two hundred and fifty (250) patients with allergic rhinoconjunctivitis with, or without asthma and sensitized to Results: Significant improvement was found after 3 months of treatment regarding CSMS (p < 0.0001) and ACT (p < 0.0001). Additionally, a significant decrease in medication consumption was found after 3 months of treatment (p < 0.0001). Adverse reactions, either local or systemic were mild and no severe reactions related to the vaccines were observed. Conclusion: After 12 months of allergen immunotherapy, glutaraldehyde-modified mixture of

Indexed as

Allergic rhino-conjunctivitisGlutaraldehyde-polymerized extractsHouse dust mitesImmunotherapy

Identifiers

PMID36119655
PMCPMC9467880
OpenAlexW4295123370

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.