Evidence map›Paper›PMID 36119550›Full record

ArticleJournal of frailty, sarcopenia and falls2022

Moderate to vigorous physical activity, leucine, and protein intake contributions to muscle health in middle age.

Kara A Stone, Allison M Barry, Christopher J Kotarsky, Nathan D Dicks, Sherri N Stastny, Wonwoo Byun, Steven Mitchell, Ryan McGrath, Kyle J Hackney

Abstract read
In one paragraph

Article in Journal of frailty, sarcopenia and falls, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Kara A StoneDepartment of Kinesiology and Health Studies, University of Central Oklahoma, Edmond, OK, USA.
Allison M BarryHealth, Human Performance, and Recreation Department, Pittsburg State University, Pittsburg, KS, USA.
Christopher J KotarskyDepartment of Health and Human Physiological Sciences, Skidmore College, Saratoga Springs, NY, USA.
Nathan D DicksNutrition, Dietetics, and Exercise Science Department, Concordia College, Moorhead, MN, USA.
Sherri N StastnyDepartment of Health, Nutrition, and Exercise Sciences, North Dakota State University, Fargo, ND, USA.
Wonwoo ByunDepartment of Health, Kinesiology, and Recreation, The University of Utah, Salt Lake City, UT, USA.
Steven MitchellDepartment of Health, Nutrition, and Exercise Sciences, North Dakota State University, Fargo, ND, USA.
Ryan McGrathDepartment of Health, Nutrition, and Exercise Sciences, North Dakota State University, Fargo, ND, USA.
Kyle J HackneyDepartment of Health, Nutrition, and Exercise Sciences, North Dakota State University, Fargo, ND, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: Identify contributors to differences in the muscle size and strength of sedentary and active young and middle-aged adults. Methods: This cross-sectional study included 98 participants aged 20-65 years. Participants were categorized based on age and self-reported physical activity (PA) habits. Participants completed a strength assessment of knee extensors (KEPT), knee flexors (KFPT), plantar flexors (PFPT), and dorsiflexors (DFPT), a 3-day dietary intake log, 7-day accelerometry, and a magnetic resonance imaging (MRI) scan for muscle cross-sectional area analysis of the right quadriceps (CSAq). Results: There were significant age and activity-related group effects for relative protein intake (p<0.001), relative energy intake (p=0.04), KEPT (p=0.01), CSAq (p=0.002), PFPT (p=0.004) and DFPT (p=0.003). Moderate, moderate-to-vigorous, and vigorous PA were positively associated with CSAq (R Conclusion: Muscle size and strength were lower in middle age relative to younger age, but increased PA, protein intake, and leucine intake was associated with the preservation of muscle size and strength in larger muscle groups of the lower body.

Indexed as

Aging muscleLeucineMiddle-agePhysical activityProtein

Identifiers

PMID36119550
PMCPMC9433941

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.