ReviewFrontiers in oncology2022
An overview of the irreversible electroporation for the treatment of liver metastases: When to use it.
Review in Frontiers in oncology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
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Who cites it
14 citing papers in PubMed, 20 citations in OpenAlex.
- Advances in the Therapeutic Landscape of Hepatocellular Carcinoma: Current Strategies and Future Perspectives.Cancers · 2026Review
- Pulsed Field Ablation in Patients With Cardiac Implantable Electric Devices: Vigilance Is Warranted.Pacing and clinical electrophysiology : PACE · 2026Review
- Mechanism and applications of magnetoelectric nanoparticles in cancer therapy.Nanomedicine (London, England) · 2025Review
- Article
- Presentation of osteoid osteoma in the fifth metatarsal: a case report and review of the literature.Journal of medical case reports · 2025Review
- Radiomics Beyond Radiology: Literature Review on Prediction of Future Liver Remnant Volume and Function Before Hepatic Surgery.Journal of clinical medicine · 2025Review
- Modern therapeutic approaches for hepatic tumors: progress, limitations, and future directions.Discover oncology · 2025Review
- Irreversible electroporation for metastatic pancreatic carcinoma with liver metastasis: What does the evidence say.World journal of clinical cases · 2025Article
- Technical aspects, methodological challenges, and factors predicting outcomes of percutaneous ablation for colorectal liver metastases.Polish journal of radiology · 2025Review
- Catalytic Degradation of Organic Dyes Indicates Anti-Proliferative Effects of Magnetoelectric Nanoparticles.Journal of electronic materials · 2025Article
- Osteoid osteoma of third metatarsal bone treated with radiofrequency ablation: Case report, imaging findings and review of the literature.Radiology case reports · 2024Article
- Configuring thermal ablation volumes for treatment of distinct tumor shapes: a repeatability study using a robotic approach.Frontiers in oncology · 2024Article
- Predictive Factors of Local Recurrence after Colorectal Cancer Liver Metastases Thermal Ablation.Journal of imaging · 2023Article
- A Retrospective Comparison of CT Imaging and Computational Simulations of Irreversible Electroporation in the Liver.Technology in cancer research & treatmentArticle
Corrections and comments
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Authors and funding
8 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Tumour ablation is an established therapy for local treatment of liver metastases and hepatocellular carcinoma. Most commonly two different kind of thermic ablation, radiofrequency ablation and microwave ablation, are used in clinical practice. The aim of both is to induce thermic damage to the malignant cells in order to obtain coagulative necrosis of the neoplastic lesions. Our main concerns about these procedures are the collateral thermic damage to adjacent structures and heat-sink effect. Irreversible electroporation (IRE) is a recently developed, non-thermal ablation procedure which works applying short pulses of direct current that generate an electric field in the lesion area. The electric field increase the transmembrane potential, changing its permeability to ions.Irreversible electroporation does not generate heat, giving the chance to avoid the heat-sink effect and opening the path to a better treatment of all the lesions located in close proximity to big vessels and bile ducts. Electric fields produced by the IRE may affect endothelial cells and cholangiocytes but they spare the collagen matrix, preserving re-epithelization process as well as the function of the damaged structures. Purpose of the authors is to identify the different scenarios where CT-guided percutaneous IRE of the liver should be preferred to other ablative techniques and why.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.